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Assessment of orbital blood flow velocities in retinopathy of prematurity

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Abstract

The purpose of this study is to evaluate whether the presence of any stage retinopathy of prematurity (ROP) alters central retinal artery (CRA) and ophthalmic artery (OA) blood flow parameters in premature infants. The patients were divided into two groups according to the development of ROP; those who have ROP were defined as group I, those without ROP were defined as group II. Ninety eyes of 45 patients in group I and 40 eyes of 20 patients in group II were investigated. The blood flows in the CRA and OA were measured using ultrasound color doppler imaging (CDI) that allows to evaluate the peak systolic velocity (PSV), end diastolic velocity (EDV), and resistivity index (RI). The results were compared between two groups of subjects. There were no significant differences in the PSV, EDV, and RI of CRA between two groups (P = 0.09, P = 0.20 and P = 0.63, respectively). The mean PSV value of OA in group I was found to be significantly higher than the one in group II (P < 0.05), but there were no significant differences in the mean EDV and RI values of OA between two groups (P = 0.40, P = 0.17 respectively). The subgroup analysis revealed that the ocular blood dynamics were not found to be significant between eyes with stage I ROP and eyes with stage II ROP (P > 0.05), whereas the difference in the mean PSV values of OA were found to be significant among the eyes with stage 1 ROP, eyes with stage 2 ROP, and eyes without ROP (P = 0.03). This study demonstrated significant alterations in systolic flow velocities in the OA predicted by CDI in infants with ROP.

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Authors and Affiliations

  1. Ophthalmology Department, Ministry of Health Sanliurfa Education and Research Hospital, Sanliurfa, Turkey

    Pehmen Yasin Ozcan

  2. Radiology Department, Ministry of Health Sanliurfa Children’s Hospital, Sanliurfa, Turkey

    Ferit Dogan

  3. Ophthalmology Department, Ministry of Health Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey

    Kenan Sonmez

  4. Ophthalmology Department, Ministry of Health Sanliurfa Maternity and Women’s Health Hospital, Sanliurfa, Turkey

    Rahim Con & Eyüp Sabri Seyhanli

  5. Department of Radiology, Harran University Medical School, Sanliurfa, Turkey

    Dilek Sen Dokumaci

  6. Department of Emergency Medicine, Ministry of Health Sanliurfa Maternity and Women’s Health Hospital, Sanliurfa, Turkey

    Eyüp Sabri Seyhanli

Authors
  1. Pehmen Yasin Ozcan
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  2. Ferit Dogan
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  3. Kenan Sonmez
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  4. Rahim Con
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  5. Dilek Sen Dokumaci
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  6. Eyüp Sabri Seyhanli
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Correspondence to Pehmen Yasin Ozcan.

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Ozcan, P.Y., Dogan, F., Sonmez, K. et al. Assessment of orbital blood flow velocities in retinopathy of prematurity. Int Ophthalmol 37, 795–799 (2017). https://doi.org/10.1007/s10792-016-0333-1

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  • DOI: https://doi.org/10.1007/s10792-016-0333-1

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