Abstract
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon disease most frequently occurring in the head and neck region. It occurs in all races. In spite of a clear distinction between ALHE and Kimura’s disease on histological grounds for almost 20 years now, confusion and misdiagnosis still exist to date. Three Spanish patients presented to our institution over a 6 year period with mass lesions in the superior orbit, medial orbito-nasal wall and eyelid, respectively. All patients were of Caucasian extraction and were diagnosed with epithelioid haemangioma on histological tissue analysis. We report on the history and management of these patients which resulted in good functional and cosmetic outcome with no subsequent evidence of disease recurrence.
References
Wells GC, Whimster IW (1969) Subcutaneous angiolymphoid hyperplasia with eosinophilia. Br J Dermatol 81(1):1–14
McEachren TM, Brownstein S, Jordan DR, Montpetit VA, Font RL (2000) Epithelioid hemangioma of the orbit. Ophthalmology 107(4):806–810
Buggage RR, Spraul CW, Wojno TH, Grossniklaus HE (1999) Kimura disease of the orbit and ocular adnexa. Surv Ophthalmol 44:79–91
Googe PB, Harris NL, Mihm MC Jr (1987) Kimura’s disease and angiolymphoid hyperplasia with eosinophilia: two distinct histopathological entities. J Cutan Pathol 14(5):263–271
Seregard S (2001) Angiolymphoid hyperplasia with eosinophilia should not be confused with Kimura’s disease. Acta Ophthalmol Scand 79(1):91–93
Archer KF, Hurwitz JJ, Heathcote G (1991) Orbital angiolymphoid hyperplasia with eosinophilia. Presentation as chalazion. Ophthal Plast Reconst Surg 7(3):208–221
Hendricks MW, Moore MM, Dell PC (1985) Angiolymphoid hyperplasia with eosinophilia: a case report. J Hand Surg Am 10(2):286–288
Lin B, Tan SH, Looi A (2008) Angiolymphoid hyperplasia with eosinophilia of the eyelid with spontaneous regression. Ophthal Plast Reconstr Surg 24(4):308–310
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Cunniffe, G., Alonso, T., Dinarès, C. et al. Angiolymphoid hyperplasia with eosinophilia of the eyelid and orbit: the Western cousin of Kimura’s disease?. Int Ophthalmol 34, 107–110 (2014). https://doi.org/10.1007/s10792-013-9741-7
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DOI: https://doi.org/10.1007/s10792-013-9741-7