Abstract
To describe the results of non-Descemet stripping automated endothelial keratoplasty (non-DSAEK). Retrospective, interventional, consecutive clinical case series. Twenty-three patients underwent non-DSAEK from January 2010 to February 2011. The various indications were pseudophakic corneal edema, aphakic corneal edema, failed graft, iridocorneal endothelial syndrome and congenital glaucoma. Corneal edema cleared in all patients within 1–4 weeks. Mean follow-up duration was 7.6 months. Post-operative best corrected visual acuity ranged from 20/400 to 20/40. Fourteen patients had co-morbid factors affecting the vision. No patient had interface haze. Immediate post-operative complications were partial graft detachment (1 patient) and secondary angle closure (1 patient). Corneal clarity was restored following secondary interventions. One late post-operative complication was graft rejection at 6 months, leading to graft failure. Non-DSAEK is a safe and viable option in cases of corneal decompensation when the Descemet membrane is non-pathological.
Similar content being viewed by others
References
Price FW Jr, Price MO (2006) Endothelial keratoplasty to restore clarity to a failed penetrating graft. Cornea 25:895–899
Nikolic L, Jovanovic V, Lackovic V, Todorovic V (2010) Endothelial keratoplasty without Descemet’s membrane stripping: histologic and ultrastructural findings. Ophthal Res 43:56–60
Kobayashi A, Yokogawa H, Sugiyama K (2008) Non-Descemet stripping endothelial keratoplasty for endothelial dysfunction secondary to argon laser iridotomy. Am J Ophthalmol 146:543–549
Chaurasia S, Muralidhar R, Murthy S, Garg P, Sangwan V (2011) Endothelial keratoplasty without stripping the Descemet’s membrane. Br J Ophthalmol 95(10):1473–1474
Price MO, Price FW Jr (2010) Endothelial keratoplasty—a review. Clin Experiment Ophthalmol 38(2):128–140
Dobbins KR, Price FW Jr, Whitson WE (2000) Trends in the indications for penetrating keratoplasty in the Midwestern United States. Cornea 19:813–816
Acknowledgments
Hyderabad Eye Research Foundation and Hyderabad Eye Institute. The authors do not have any financial interest or any conflicting relationship in any of the issues or products referred to in the manuscript.
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chaurasia, S., Ramappa, M. & Sangwan, V.S. Clinical outcomes of non-Descemet stripping automated endothelial keratoplasty. Int Ophthalmol 32, 571–575 (2012). https://doi.org/10.1007/s10792-012-9615-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10792-012-9615-4