Abstract
Indications for the Boston keratoprosthesis differ throughout the world depending on the prevailing regional causes of end-stage corneal disease. We report the short term anatomical and functional outcomes of the Boston type 1 keratoprosthesis for severe bilaterally blinding vernal keratoconjunctivitis and Mooren’s ulcer. A retrospective chart review was conducted of 2 patients who underwent several unsuccessful ocular surface reconstruction procedures before Boston type 1 keratoprosthesis implantation. The anatomical and visual outcomes of the Boston type 1 keratoprosthesis at 1 year of follow-up were assessed clinically and by anterior segment optical coherence tomography imaging. The keratoprosthesis was retained in both the eyes at 1 year postoperatively with a best-corrected visual acuity of 20/30 in both patients. To our knowledge this is the first report of successful Boston keratoprosthesis implantation for these two unusual indications.
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References
Aquavella JV, Qian Y, McCormick GJ, Palakuru JR (2005) Keratoprosthesis: the Dohlman-Doane device. Am J Ophthalmol 140:1032–1038
Aldave AJ, Kamal KM, Vo RC et al (2009) The Boston type I keratoprosthesis: improving outcomes and expanding indications. Ophthalmology 116:640–651
Zerbe BL, Belin MW, Ciolino JB (2006) Boston type 1 keratoprosthesis study group. Results from the multicenter Boston type 1 keratoprosthesis study. Ophthalmology 113:1779–1780
Cauchi PA, Ang GS, Azuara-Blanco A et al (2008) A systematic literature review of surgical interventions for limbal stem cell deficiency in humans. Am J Ophthalmol 146:251–259
Liang L, Sheha H, Tseng SC (2009) Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits. Arch Ophthalmol 127:1428–1434
Girard LJ, Hawkins RS, Nieves R et al (1977) Keratoprosthesis: a 12-year follow-up. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol 83:252–267
Khan BF, Harissi-Dagher M, Khan DM et al (2007) Advances in Boston keratoprosthesis: enhancing retention and prevention of infection and inflammation. Int Ophthalmol Clin 47:61–71
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This study was supported by the Hyderabad Eye Research Foundation.
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Basu, S., Taneja, M. & Sangwan, V.S. Boston type 1 keratoprosthesis for severe blinding vernal keratoconjunctivitis and Mooren’s ulcer. Int Ophthalmol 31, 219–222 (2011). https://doi.org/10.1007/s10792-011-9438-8
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DOI: https://doi.org/10.1007/s10792-011-9438-8