Abstract
We have measured terahertz and powder x-ray diffraction spectra of D-histidine, L-histidine, and DL-histidine. The as-received D and L material exists in two different polymorphs: D-histidine is in the metastable monoclinic form, while L-histidine is in the stable orthorhombic form. For both the L and D enantiomers, recrystallization of the as-received material results in a mixture of the monoclinic and orthorhombic forms.
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Acknowledgements
We acknowledge the National Science Foundation (CHE-0911593) and AstraZeneca for partial support of this work. KS thanks the German Academic Exchange Service (DAAD) for funding.
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True, A.B., Schroeck, K., French, T.A. et al. Terahertz Spectroscopy of Histidine Enantiomers and Polymorphs. J Infrared Milli Terahz Waves 32, 691–698 (2011). https://doi.org/10.1007/s10762-010-9645-9
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DOI: https://doi.org/10.1007/s10762-010-9645-9