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Common Pathogenesis of Acne Vulgaris and Atherosclerosis

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Abstract

Foam cells are lipid-loaded macrophages and neutrophils that are generated from a massive uptake of oxidized lipid. Foam cells are a pathological hallmark of atherosclerosis, and have also been found in acne lesions. The same pathological changes determine the common pathogenesis. According to the pathological function of foam cells in these lesions, we put forward a viewpoint on the pathogenesis of acne and atherosclerotic plaques.

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Authors and Affiliations

  1. Laboratory of Medical Molecular Biology & Research Department, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Dongge Road No.89-9, Nanning City, Guangxi, China

    Hao Jiang

  2. Dermatological Department & Dongge Outpatient Department, The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning City, Guangxi, China

    Changyi Li

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  1. Hao Jiang
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Correspondence to Hao Jiang.

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Jiang, H., Li, C. Common Pathogenesis of Acne Vulgaris and Atherosclerosis. Inflammation 42, 1–5 (2019). https://doi.org/10.1007/s10753-018-0863-y

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