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The ApoB/ApoA1 Ratio is Associated with Metabolic Syndrome and its Components in a Chinese Population

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Abstract

In this study, we assessed whether the apolipoprotein B/apolipoprotein A1 ratio (ApoB/ApoA1) is related to metabolic syndrome (MS) and its components in an urban Chinese population. A total of 709 community residents were enrolled. Metabolic syndrome was defined according to the International Diabetes Federation definition in 2005. The high ApoB/ApoA1 group was defined as the gender-specific upper quartile of the ApoB/ApoA1 ratio. Insulin resistance (IR) was defined as the upper quartile of Homa-IR. The ApoB/ApoA1 ratio was significantly higher in subjects with MS, compared to those without (p < 0.05). After adjusting for age and gender, subjects with MS (odds ratio [OR] = 3.5) or IR (OR = 2.3) were more likely to be in the high ApoB/ApoA1 group. The ApoB/ApoA1 ratio increased significantly as the number of MS components increased (p < 0.05). Taken together, these data demonstrate that the ApoB/ApoA1 ratio is strongly associated with MS and its components in an urban Chinese population.

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Authors and Affiliations

  1. Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Street, Chongqing, 400016, China

    Li Zhong, Qifu Li, Yuanjuan Jiang, Dan Cheng, Zhoujun Liu, Bangqiong Wang, Qingfeng Cheng & Hua Qing

  2. Medical Examination Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China

    Rong Luo

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  1. Li Zhong
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  2. Qifu Li
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  3. Yuanjuan Jiang
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  4. Dan Cheng
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  5. Zhoujun Liu
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  6. Bangqiong Wang
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  7. Rong Luo
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  8. Qingfeng Cheng
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  9. Hua Qing
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Correspondence to Qifu Li.

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Zhong, L., Li, Q., Jiang, Y. et al. The ApoB/ApoA1 Ratio is Associated with Metabolic Syndrome and its Components in a Chinese Population. Inflammation 33, 353–358 (2010). https://doi.org/10.1007/s10753-010-9193-4

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  • DOI: https://doi.org/10.1007/s10753-010-9193-4

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