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Effects of Haematococcus pluvialis supplementation on antioxidant system and metabolism in rainbow trout (Oncorhynchus mykiss)

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Abstract

Effects of commercial source for astaxanthin (Haematococcus pluvialis) (H.p) on antioxidant power, specific marker enzymes, and some metabolites were examined in rainbow trout (Oncorhynchus mykiss). Fish were fed on diets containing 1, 3, and 10 g microalga kg−1 feed for 30 days. Serum total antioxidant activity and lipid peroxidation product, indicated by malondialdehyde (MDA), significantly enhanced with different doses of administration, indicating the elevated antioxidant status in all treatment groups. In group fed with high dose of alga, significantly elevated aspartate aminotransferase activity (AST) was noted, indicating damage of normal liver function in this group. Alkaline phosphatase (ALP) and alanine aminotransferase (ALT) were not affected in all groups. Although serum total protein remained unaffected, serum glucose level was decreased significantly in lower doses of administration. Furthermore, triglyceride and cholesterol levels showed significant decrease in 3 g kg−1 microalga group by modulation of lipid metabolism in this group. On the other hand, in highest dose, significant increase in lipids was observed, indicating the slight dysfunction in lipid metabolism in this treatment group. The present study suggests that Haematococcus pluvialis especially in dose of 3 g kg−1 feed administration may effectively enhance the antioxidant system and some biochemical parameters in rainbow trout.

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Acknowledgments

We thank Mr. Daryabarii for providing juvenile rainbow trout and ponds for this project. Thanks are also due to research affairs of University of Tabriz, Iran.

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Authors and Affiliations

  1. Department of Food Hygiene and Aquatic Animals, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

    Najmeh Sheikhzadeh

  2. Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

    Hossein Tayefi-Nasrabadi

  3. Department of Fisheries, North Tehran Branch, University of Marine Sciences and Techniques, Tehran, Iran

    Ali Khani Oushani & Mohammad Hamed Najafi Enferadi

Authors
  1. Najmeh Sheikhzadeh
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  2. Hossein Tayefi-Nasrabadi
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  3. Ali Khani Oushani
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  4. Mohammad Hamed Najafi Enferadi
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Correspondence to Najmeh Sheikhzadeh.

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Sheikhzadeh, N., Tayefi-Nasrabadi, H., Khani Oushani, A. et al. Effects of Haematococcus pluvialis supplementation on antioxidant system and metabolism in rainbow trout (Oncorhynchus mykiss). Fish Physiol Biochem 38, 413–419 (2012). https://doi.org/10.1007/s10695-011-9519-7

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  • DOI: https://doi.org/10.1007/s10695-011-9519-7

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