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A model study by using polymeric molecular imprinting nanomaterials for removal of penicillin G

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Abstract

We aimed to develop a molecularly imprinted polymeric systems with using penicillin G as a template molecule for removal of the antibiotic residues from environmental samples. Firstly, Pen-G-imprinted poly (2-hydroxyethyl methacrylate-N-methacryloyl-l-alanine) [p(HEMA-MAAL)] nanopolymers were synthesized by surfactant-free emulsion polymerization method. Then, template molecule (Pen-G) was extracted from nanopolymers. Synthesized nanopolymers were characterized by different methods such as Fourier-transform infrared spectroscopy (FTIR), elemental and zeta-size analysis, scanning electron microscope (SEM), and surface area calculations. Nanopolymers have 60.38 nm average size and 1034.22 m2/g specific surface area. System parameters on Pen-G adsorption onto Pen-G imprint nanopolymers were investigated at different conditions. The specific adsorption value (Qmax) of molecularly impirinted p(HEMA-MAAL) nanopolymers was found 71.91 g/g for Pen-G in 5 mg/mL Pen-G initial concentration. Pen-G adsorption of molecularly imprinted nanopolymers was 15 times more than non-imprinted polymer. It is shown that obtained p(HEMA-MAAL) nanopolymer was a reuseable product which protected its adsorption capacity of 98.9% after 5th adsorption-desorption cycle. In conclusion, we suggest a method to develop a nanostructure, selective, low-cost molecularly imprinted polymeric systems with using penicillin G as a template molecule for removal of the antibiotic residues.

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Acknowledgments

This study was performed with financial support from Ege University Scientific Research Project Coordination (Project no.12/FEN/029).

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Authors and Affiliations

  1. Department of Biochemistry, Ege University Faculty of Science, Izmir, Turkey

    Cansu Ilke Kuru, Fulden Ulucan & Sinan Akgöl

  2. Turkish Health of Ministry, Turkish Medicines and Medical Devices Agency, Ankara, Turkey

    Kevser Kuşat

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  1. Cansu Ilke Kuru
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Correspondence to Sinan Akgöl.

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Kuru, C.I., Ulucan, F., Kuşat, K. et al. A model study by using polymeric molecular imprinting nanomaterials for removal of penicillin G. Environ Monit Assess 192, 367 (2020). https://doi.org/10.1007/s10661-020-08294-2

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