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RETRACTED ARTICLE: Lead poisoning in Nile tilapia (Oreochromis niloticus): oxidant and antioxidant relationship

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This article was retracted on 07 December 2016

Abstract

Selenium and vitamin E are very effective antioxidant agents which play important roles in improving and development of aquaculture sector. This study was conducted to determine the protective and treatment effects of vitamin E and selenium against lead toxicity. Administration of both vitamin E and selenium ameliorated the adverse effects of lead acetate toxicity through significant increase in hemoglobin, packed cell volume, RBC count, WBC count, and lymphocytes compared to lead acetate-exposed groups especially after the 10th week. Also, it is revealed that severe decrease of total protein, calcium, phosphorous, and magnesium in lead acetate intoxicated group. On contrary, significant increase of blood parameters upon addition of vitamin E and selenium combined with/without lead. On the other hand, insignificant decreases of sAST, sALT, urea, and creatinine in group fed on vitamin E and selenium, while increase in lead acetate intoxicated group. Lead acetate caused increasing of lipid peroxidation level (malondialdehyde) and decreasing of superoxide dismutase activity and reduced glutathione level. From these results, it is concluded that exposure to lead acetate is considered as hepatotoxic environmental pollutant. Exposure to lead acetate induced significant effects on antioxidant status. Antioxidants (vitamin E and selenium) showed important roles to protect body against lipid peroxidation, which considered as the first step of cell membrane damage, in addition to the improvement of the endogenous antioxidant enzyme activities.

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This study was funded by the author.

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The author declares that he has no conflict of interest.

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Authors and Affiliations

  1. Department of Poultry and Fish diseases, Faculty of Veterinary Medicine, Alexandria University, Edfina, Rosetta, 22758, Egypt

    Mahmoud Tanekhy

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  1. Mahmoud Tanekhy
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Correspondence to Mahmoud Tanekhy.

Additional information

This article has been retracted at the request of the Editor-in-Chief. A complaint received against it indicated that it had very high levels of similarity to text, study design and figures with the following article:

Nephroprotective and antioxidant significance of selenium and α-tocopherol on lead acetate-induced toxicity of Nile Tilapia (Oreochromis niloticus), (2015), Hashish, E.A., Elgaml, S.A., El-Murr, A., Khalil, R, 41: 651. Fish Physiology and Biochemistry, June 2015, Volume 41, Issue 3, pp 651-660.

An investigation carried out by the Vice President of Graduate Studies and Research at Alexandria University found that the research presented in the EMAS paper by Mahmoud Tanekhy was published without the consent of the original owners of the work - Dr. Ryad Khalil (Alexandria University) and Drs. Emad A. Hashish, Dr. Shimaa A. Elgaml and Dr. Abdelhakeem El-Murr (Zagazig University).

An erratum to this article is available at http://dx.doi.org/10.1007/s10661-016-5715-3.

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Tanekhy, M. RETRACTED ARTICLE: Lead poisoning in Nile tilapia (Oreochromis niloticus): oxidant and antioxidant relationship. Environ Monit Assess 187, 154 (2015). https://doi.org/10.1007/s10661-015-4387-8

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