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Cardiovascular disease incidence and survival: Are migrants always worse off?

  • CARDIOVASCULAR DISEASE
  • Published:
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Abstract

Studies on cardiovascular disease (CVD) incidence and survival show varying results between different ethnic groups. Our aim was to add a new dimension by exploring the role of migrant status in combination with ethnic background on incidence of—and survival from—CVD and more specifically acute myocardial infarction (AMI) and stroke. We conducted a historically prospective cohort study comprising all newly-arrived migrants to Denmark between 1.1.1993 and 31.12.2010 (n = 114,331), matched 1:6 to Danish-born by age and sex. CVD incidence was retrieved from the National Patient Registry and differences in incidence were assessed by Poisson regression and stratified by sex. Survival differences were assessed by Cox regression using all-cause and cause-specific mortality as outcome. Male refugees had significantly lower incidence of CVD (RR = 0.89; 95 % CI 0.85–0.93) and stroke (IRR = 0.62; 95 % CI 0.56–0.69) compared to Danish-born, but significantly higher incidence of AMI (IRR = 1.12; 95 % CI 1.02–1.24). Female refugees had similar rates of CVD and AMI, but significantly lower incidence of stroke (RR = 0.76; 95 % CI 0.67–0.85). Both male and female family-reunified immigrants had significantly lower incidence of CVD, AMI and stroke. All-cause and cause-specific survival after CVD, AMI and stroke was similar or significantly better for migrants compared to Danish-born, regardless of type of migrant (refugee vs. family-reunified) or country of origin. Refugees are disadvantaged in terms of some types of cardiovascular disease compared to Danish-born. Family-reunified migrants on the other hand had lower rates of CVD. All migrants had better survival than Danish-born indicating that migrants may not always be disadvantaged in health.

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References

  1. Kunst A, Stronks K, Agyemang C (2011) Non-communicable diseases. In: Rechel B, Mladowsky P, Devillé W, Rijks B, Petrova-Benedict R, McKee M (eds) Migration and health in the European union: European observatory on health systems and policies.

  2. Bhopal R, Rafnsson SB, Agyemang C, Fagot-Campagna A, Giampoli S, Hammar N, Harding S, Hedlund E, Juel K, Mackenbach JP, Primatesta P, Rey G, Rosato M, Wild S, Kunst AE. Mortality from circulatory diseases by specific country of birth across six European countries: test of concept. Euro J Public Health. 2011;22(3):353–9.

    Article  Google Scholar 

  3. International Migration Report 2009: A global assesment. New York: United Nations, 2011:18.

  4. Bhopal R. Migration, ethnicity, race and health in multicultutal societies: foundations for better epidemiology, public health, and health care, vol. 1. 1st ed. Oxford, OUP Oxford; 2007. p. 1–29.

  5. Norredam M, Nielsen SS, Krasnik A. Migrants’ utilization of somatic health care services in Europe—a systematic review. Eur J Public Health. 2009;20(5):555–63.

    Article  PubMed  Google Scholar 

  6. Hempler N, Larsen FB, Nielsen SS, Diderichsen F, Andreasen AH, Jørgensen T. A registry-based follow-up study, comparing the incidence of CVD in ethnic Danish born and immigrants born in Turkey, Pakistan and the former Yugoslavia: do social inequalities play a role? BMC Public Health. 2011;11:662.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Gadd M, Johansson SE, Sundquist J, Wändell P. The trend in cardiovascular disease in immigrants in Sweden. Eur J Epidemiol. 2005;20:755–60.

    Article  CAS  PubMed  Google Scholar 

  8. Hedlund E, Lange A, Hammar N. Acute myocardial infarction incidence in immigrants to Sweden. Country of birth, time since immigration and time trends over 20 years. Eur J Epidemiol. 2007;22(8):493–503.

    Article  PubMed  Google Scholar 

  9. Fischbacher C, Bhopal R, Povey C, Steiner M, Chalmers J, Mueller G, Jamieson, Knowles D. Record linked retrospective cohort study of 4.6 million people exploring ethnic variations in disease: myocardial infarction in South Asians. BMC Public Health. 2007;7:142.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Agyemang C, Vaartjes I, Bots ML, Van Valkengoed IG, de Munter JS, de Bruin A, Berger-van Sijl M, Reitsma JB, Stronks K. Risk of death after first admission for cardiovascular diseases by country of birth in the Netherlands: a nationwide record-linked retrospective cohort study. Heart. 2009;95:747–53.

    Article  CAS  PubMed  Google Scholar 

  11. Wilkinson P, Sayer J, Koorithottumkal L, Grundy C, Marchant B, Kopelman P, Timmis AD. Comparison of case fatality in South Asian and white patients after acute myocardial infarction: observational study. BMJ. 1996;312:1330–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Kaul P, McAlister FA, Ezekowitz JA, Grover VK, Quan H. Ethnic differences in 1-year mortality among patients hospitalised with heart failure. Heart. 2011;97:1048–53.

    Article  PubMed  Google Scholar 

  13. Wild S, Fischbacher C, Brock A, Griffiths C, Bhopal R. Mortality from all causes and circulatory disease by country of birth in England and Wales 2001–2003. J Public Health. 2007;29(2):191–8.

    Article  CAS  Google Scholar 

  14. Hedlund E, Perhsson K, Lange A, Hammar N. Country of birth and survival after a first myocardial infarction in Stockholm, Sweden. Eur J Epidemiol. 2008;23:341–7.

    Article  PubMed  Google Scholar 

  15. Indvandrere i Danmark (Immigrants in Denmark). Copenhagen: statistics Denmark, 2010.

  16. Wolfe C, Smeeton NC, Coshall C, Tilling K, Rudd AG. Survival differences after stroke in a multiethnic population: follow-up study with the South London stroke register. BMJ. 2005;331(7514):431.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Spallek J, Zeeb H, Razum O. What do we have to know from migrants’ past exposures to understand their health status? A life course approach. Emerg Themes Epidemiol. 2011;15(8):6.

    Article  Google Scholar 

  18. Norredam M, Olsbjerg M, Petersen JH, Juel K, Krasnik A. Inequalities in mortality among refugees and immigrants compared to ethnic Danish born—a historical prospective cohort study. BMC Public Health. 2012;12(1):757.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Hollander A, Bruce D, Ekberg J, Burtsröm B, Borell C, Ekblad S. Longitudinal study of mortality among refugees in Sweden. Int J Epidemiol. 2012;41(4):1153–61.

    Article  PubMed  Google Scholar 

  20. Lynge E, Sandegaard JL, Rebolj M. The Danish national patient register. Scand J Public Health. 2011;39(7):30–3.

    Article  PubMed  Google Scholar 

  21. Helweg-Larsen K. The Danish Register of Causes of Death. Scand J Public Health. 2011;39(7 suppl):26–9.

    Article  PubMed  Google Scholar 

  22. Norredam M. Migrants’ access to healthcare. Dan Med Bull. 2011;58(10):B4339.

    PubMed  Google Scholar 

  23. European cardiovascular disease statistics. 2012 ed. Brussels: European heart network and European society of cardiology 2012.

  24. Agyemang C, de-Graft AA, Bhopal R. Ethnicity and cardiovascular health research: pushing the boundaries by including comparison populations in the countries of origin. Ethn Health. 2012;17(6):579–96.

    Article  PubMed  Google Scholar 

  25. Nielsen S, Yazici S, Petersen SG, Blaakilde AL, Krasnik A. Use of cross-border healthcare services among ethnic Danes, Turkish immigrants and Turkish descendants in Denmark: a combined survey and registry study. BMC Health Serv Res. 2012;13(12):390.

    Article  Google Scholar 

  26. Nichols M, Townsend N, Scarborough P, Rayner M. Trends in age-specific coronary heart disease mortality in the European union over three decades 1980–2009. Eur Heart J. 2013;34(39):3017–27.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Razum O, Twardella D. Time travel with oliver twist—towards an explanation for a paradoxically low mortality among recent immigrants. Trop Med Int Health. 2002;7(1):4–10.

    Article  PubMed  Google Scholar 

  28. Johnsen S, Overvad K, Sorensen HT, Tjonneland A, Husted SE. Predictive value of stroke and transient ischemic heart attack discharge diagnosis in the Danish national registry of patients. J Clin Epidemiol. 2002;55(6):602–7.

    Article  PubMed  Google Scholar 

  29. Rix T, Riahi S, Overvad K, Lundbye-Christensen S, Schmidt EB, Joensen AM. Validity of the diagnoses atrial fibrillation and atrial flutter in a Danish patient registry. Scand Cardiovasc J. 2012;46(3):149–53.

    Article  PubMed  Google Scholar 

  30. Madsen M, Davidsen M, Rasmussen S, Abildström SZ, Osler M. The validity of the diagnosis of acute myocardial infarction in routine statistics: a comparison of mortality and hospital discharge data with the Danish MONICA registry. J Clin Epidemiol. 2003;56(2):124–30.

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors wish to thank Amina Barghadouch for her contribution to the paper.

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None declared.

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Correspondence to Stine Byberg.

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Byberg, S., Agyemang, C., Zwisler, A.D. et al. Cardiovascular disease incidence and survival: Are migrants always worse off?. Eur J Epidemiol 31, 667–677 (2016). https://doi.org/10.1007/s10654-015-0024-7

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  • DOI: https://doi.org/10.1007/s10654-015-0024-7

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