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A graphical study of tuberculosis incidence and trends in the WHO’s European region (1980–2006)

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Abstract

A graphical output was obtained using classical principal component analysis techniques in order to analyse tuberculosis trends in Europe over a 27-year period (1980–2006). Taxonomic methods were used to better define the interrelationship between the data in the 52 countries studied. Data were provided by the World Health Organization. Differences in the overall incidence and trends were identified during the 1980–2006 period. The highest rates of incidence were reported in Kazakhstan, Bosnia and Herzegovina, Romania and Kyrgyzstan. High and moderately high rates were reported in the former Soviet Union, the former Yugoslavia, some countries from the former Eastern Bloc, Turkey and Portugal. The lowest rates were reported in the eastern Mediterranean, Scandinavia and Iceland. Risk of infection was determined by social conditions, intravenous drug use, HIV infection and immigration from countries where tuberculosis is endemic. As regards development of tuberculosis in Europe, 1992 represents the change in the decreasing trend in the incidence observed from 1980, when the incidence presented a minimum general trend and started to increase. The linear model calculated to project the rate of increase from 2006 to 2015, reveals the tuberculosis rates observed during the 1980s.

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Notes

  1. Ab: Albania, An: Andorra, Ar: Armenia, At: Austria, Az: Azerbaijan, Bl: Belarus, Be: Belgium, Bh: Bosnia and Herzegovina, Bg: Bulgaria, Cr: Croatia, Cy: Cyprus, Cz: Czech Republic, Dk: Denmark, Ee: Estonia, Fi: Finland, Fr: France, Go: Georgia, De: Germany, Gr: Greece, Hu: Hungary, Ic: Iceland, Ie: Ireland, Is: Israel, It: Italy, Ka: Kazakhstan, Ky: Kyrgyzstan, Lv: Latvia, Lt: Lithuania, Lu: Luxembourg, Mt: Malta, Mo: Monaco, Nl: Netherlands, No: Norway, Pl: Poland, Pt: Portugal, Rm: Republic of Moldova, Ro: Romania, Ru: Russian Federation, So: San Marino, Sm: Serbia and Montenegro, Sk: Slovakia, Sl: Slovenia, Es: Spain, Se: Sweden, Ch: Switzerland, Ta: Tajikistan, Yu: The former Yugoslav-Republic of Macedonia, Tr: Turkey, Tu: Turkmenistan, Ur: Ukraine, Uk: United Kingdom, Uz: Uzbekistan, Av: Average country.

Abbreviations

WHO:

World health organization

PCA:

Principal component analysis

NJCA:

Neighbour-joining cluster analysis

UPGMA:

Unweighted pair-group method with arithmetic mean

References

  1. Raviglione MC, Snider DE, Kochi A. Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. JAMA. 1995;273:220–6. doi:10.1001/jama.273.3.220.

    Article  PubMed  CAS  Google Scholar 

  2. Dye C, Watt CJ, Bleed DM, Mehran S, Raviglione MC. Evolution of tuberculosis control and prospects for reducing tuberculosis incidence, prevalence and deaths globally. JAMA. 2005;293:2767–75. doi:10.1001/jama.293.22.2767.

    Article  PubMed  CAS  Google Scholar 

  3. Raviglione MC, Sudre P, Rieder HL, Spinaci S, Kochi A. Secular trends of tuberculosis in Western Europe. Bull World Health Organ. 1993;71:297–306.

    PubMed  CAS  Google Scholar 

  4. Rieder HL. Epidemiology of tuberculosis in Europe. Eur Respir J. 1995;8:620s–32s.

    Google Scholar 

  5. Sutherland I, Styblo K, Sampalik M, Bleiker MA. Annual risk of tuberculosis infection in 14 countries, derived from the results of tuberculin surveys in 1948–1952. Tuberculosis Surveillance Research Unit Report N.2. Bull Int Union Tuberc. 1971;45:75–114.

    Google Scholar 

  6. Waaler II, Gattung O, Mordal K. The risk of tuberculosis infection in Norway. Tuberculosis surveillance research unit report N.2. Bull Int Union Tuberc N.3. 1975;50:5–61.

    CAS  Google Scholar 

  7. Raviglione MC, Rieder HL, Styblo K, Khomenko AG, Esteves K, Kochi A. Tuberculosis trends in Eastern Europe and the former USSR. Document WHO/ITB/94.176, World Health Organ, 1994.

  8. Office fédéral de la santé publique. La tuberculose en Suisse 1988–1992. Bulletin de l’Office fédéral de la santé publique. 1993;41:739–45.

    Google Scholar 

  9. Haux R, Dudeck J, Gaus W, et al. Recommendations of the German association for medical informatics, biometry and epidemiology for education and training in medical informatics. Methods Inf Med. 1992;31:60–70.

    PubMed  CAS  Google Scholar 

  10. Sokal RR, Michener CD. A statistical method for evaluating systematic relationships. Univ Kans Sci Bull. 1958;28:1409–38.

    Google Scholar 

  11. Anderson TW. An introduction to multivariate statistical analysis. New York: John Wiley & Sons; 1958.

    Google Scholar 

  12. Muirhead RJ. Aspects of multivariate statistical theory. New York: John Wiley; 1982.

    Book  Google Scholar 

  13. Report WHO. Global tuberculosis control epidemiology, strategy, financing. Geneva. World Health Organization. 2009. WHO/HTM/TB/2009.411 (Available at: http://www.who.int/tb/publications/global_report/2009/en/index.html). Accessed 23 Mar 2009.

  14. Report WHO. Global Tuberculosis Control. Interim Policy on Collaborative TB/HIV Activities. Geneva. World Health Organization. 2004. WHO/HTM/TB/2004.

  15. Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol. 1987;4:406–25.

    PubMed  CAS  Google Scholar 

  16. Hammer O, Harper DAT, Ryan PD. PAST: palaentological statistics software package for education and data analysis. Palaentologica Electronica. 2001;4(1):9.

    Google Scholar 

  17. Centers for Disease Control and Prevention. Tuberculosis outbreak among homeless persons, King County Washington, 2002–2003. MMWR Morb Mortal Wkly Rep. 2003;52:1209–10.

    Google Scholar 

  18. Mayoral JM, Garcia M, Varela MC, Fernandez JC, Garcia J, Herrera D, et al. Incidente of pulmonary tuberculosis and HIV coinfection in the province of Seville, Spain, 1998. Eur J Epidemiol. 2001;17:737–42. doi:10.1023/A:1015632013465.

    Article  Google Scholar 

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Correspondence to Toni Monleón-Getino.

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Ríos, M., Monleón-Getino, T. A graphical study of tuberculosis incidence and trends in the WHO’s European region (1980–2006). Eur J Epidemiol 24, 381–387 (2009). https://doi.org/10.1007/s10654-009-9347-6

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