Abstract
A total of 170 Campylobacter jejuni strains isolated from the stool of children with clinical gastroenteritis, aged from 3 months to 14 years, were collected during a two-year period (2004–2005). From the 170 strains 30% were resistant to ciprofloxacin (MIC ≥4 μg/ml), 55% to tetracycline (MIC > 8 μg/ml), 13% to clindamycin (MIC ≥8 μg/ml), 4% to ampicillin (MIC > 16 μg/ml), 6% to erythromycin (MIC ≥8 μg/ml), 4% to coamoxiclav (MIC ≥16/8 μg/ml) and 0% to gentamicin. Compared to previous reports from Greece, the antimicrobial resistance rates to erythromycin, ampicillin and coamoxiclav remain low, while they are still high for tetracycline and ciprofloxacin. Considering similar reports from many other countries and the high incidence of Campylobacter gastroenteritis worldwide, the value of ciprofloxacin as a first choice drug␣in the empiric treatment of the infection is questionable.
References
Gaunt PN, Piddock LJV 1996 Ciprofloxacin resistant Campylobacter spp. in humans: An epidemiological and laboratory study. J Antimicrob Chemother 37: 747–57
Chatzipanagiotou S, Papavasileiou E, Lakumenta A et al. 2002 Antimicrobial susceptibility patterns of Campylobacter jejuni strains isolated from hospitalized children in Athens, Greece. J Antimicrob Chemother 49: 803–05
Wagner J, Jabbusch M, Eisenblatter M, Hahn H, Wendt C, Ignatius R. 2003 Susceptibilities of Campylobacter jejuni isolates from Germany to ciprofloxacin, moxifloxacin, erythromycin, clindamycin, and tetracycline. Antimicrob Agents Chemother 47: 2358–361
Hakanen AJ, Lehtopolku M, Siitonen A, Huovinen P, Kotilainen P 2003 Multidrug resistance in Campylobacter jejuni strains collected from Finnish patients during 1995–000. J Antimicrob Chemother 52: 1035–039
Garcia-Campos JA, Alarcon T, Domingo D, Menendez-Rivas M, Lopez-Brea M. 2003 Susceptibility of Campylobacter jejuni clinical isolates from children to eight antibiotics. Rev Esp Quimioter 16: 216–20
Gaundreau C, Gilbert H. 2003 Antimicrobial resistance of Campylobacter jejuni subsp. jejuni isolated from humans in 1998 to 2001 in Montreal, Canada. Antimicrob Agents Chemother 47: 2017–019
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Papavasileiou, E., Voyatzi, A., Papavasileiou, K. et al. Antimicrobial susceptibilities of Campylobacter jejuni isolates from hospitalized children in Athens, Greece, collected during 2004–2005. Eur J Epidemiol 22, 77–78 (2007). https://doi.org/10.1007/s10654-006-9080-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10654-006-9080-3