Abstract
Mathematical models have been recognized as powerful tools for providing new insights into the understanding of viral dynamics of human diseases at both the population and cellular levels. This article briefly reviews the role of mathematical models and␣their historical precedents for creating new knowledge of the mechanisms of disease pathogenesis, transmission, and control of some human viral infections. Future research in the modelling of infectious diseases will need to rely upon incorporation of the fundamental principles that govern viral dynamics in vivo as well as in the population.
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Acknowledgements
This work was supported in part by the Natural Sciences and Engineering Research Council of Canada (NSERC). The author would like to thank Dr M.E. Alexander and A.R. Summers for discussion and useful comments during the development of this article. The author is grateful to the reviewers for insightful comments. The author also would like to dedicate this article to Professor P.N. Shivakumar on the occasion of his 70th birthday.
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Moghadas, S.M. Gaining insights into human viral diseases through mathematics. Eur J Epidemiol 21, 337–342 (2006). https://doi.org/10.1007/s10654-006-9007-z
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DOI: https://doi.org/10.1007/s10654-006-9007-z