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Lifetime Alcohol Drinking Pattern is Related to the Prevalence of Metabolic Syndrome. The Western New York Health Study (WNYHS)

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Abstract

The association of lifetime alcohol drinking pattern with the prevalence of the metabolic syndrome is largely unknown. Analyses were conducted on a population-based sample in a cross-sectional study (N = 2818, ages 35–79 years, 93% whites). Included were subjects who drank at least once a month for a period of at least six months during their lifetimes and were free of cardiovascular disease and cancer at the time of interview. Lifetime drinking measures included total years of drinking, total drinking days, volume (total drinks) and average intensity (#drinks/drinking day); frequency of intoxication and heavy drinking; and age drinking began and ended. Metabolic syndrome components included impaired fasting glucose (IFG), high triglycerides (HTG), low HDL cholesterol (LHDLC), abdominal obesity (ABO), and hypertension (HBP). Potential confounders examined were age, gender, race, family history of coronary heart disease or diabetes, years of education, lifetime and current cigarette smoking, current drinking status, physical activity, and dietary factors. Multiple logistic regressions indicated that average intensity was directly related to IFG, HTG, HBP, and metabolic syndrome overall (p for linear trend = 0.03, 0.04, 0.003, and 0.009, respectively) and to ABO in women only (p for trend = 0.0004). Prevalence ratios (95% CI) for the metabolic syndrome according to quartiles of intensity were 1.00 (lowest), 1.23 (0.91–1.67), 1.43 (1.06–1.91) and 1.60 (1.12–2.30). Total drinking days was inversely related to LHDLC (p for trend = 0.0002) and to ABO in women only (p for trend < 0.0001). It is concluded that lifetime drinking patterns are significantly related to the prevalence of the metabolic syndrome.

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References

  1. G Reaven (2002) ArticleTitleMetabolic syndrome: pathophysiology and implications for management of cardiovascular disease Circulation 106 286–288 Occurrence Handle10.1161/01.CIR.0000019884.36724.D9 Occurrence Handle12119239

    Article  PubMed  Google Scholar 

  2. B Isomaa P Almgren T Tuomi et al. (2001) ArticleTitleCardiovascular morbidity and mortality associated with the metabolic syndrome Diabetes Care 24 683–689 Occurrence Handle1:STN:280:DC%2BD3MvjsVOqsw%3D%3D Occurrence Handle11315831

    CAS  PubMed  Google Scholar 

  3. HM Lakka DE Laaksonen TA Lakka et al. (2002) ArticleTitleThe metabolic syndrome and total and cardiovascular disease mortality in middle-aged men Jama 288 2709–2716 Occurrence Handle10.1001/jama.288.21.2709 Occurrence Handle12460094

    Article  PubMed  Google Scholar 

  4. ES Ford WH Giles WH Dietz (2002) ArticleTitlePrevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey Jama 287 356–359 Occurrence Handle10.1001/jama.287.3.356 Occurrence Handle11790215

    Article  PubMed  Google Scholar 

  5. L Djousse DK Arnett JH Eckfeldt MA Province MR Singer RC Ellison (2004) ArticleTitleAlcohol consumption and metabolic syndrome: Does the type of beverage matter? Obes Res 12 1375–1385 Occurrence Handle15483202

    PubMed  Google Scholar 

  6. YS Yoon SW Oh HW Baik HS Park WY Kim (2004) ArticleTitleAlcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey Am J Clin Nutr 80 217–224 Occurrence Handle1:CAS:528:DC%2BD2cXltlKltLY%3D Occurrence Handle15213051

    CAS  PubMed  Google Scholar 

  7. S Linn M Carroll C Johnson R Fulwood W Kalsbeek R Briefel (1993) ArticleTitleHigh-density lipoprotein cholesterol and alcohol consumption in US white and black adults: data from NHANES II Am J Public Health 83 811–816 Occurrence Handle1:STN:280:ByyB2s%2Fhslw%3D Occurrence Handle8498617

    CAS  PubMed  Google Scholar 

  8. I Kato Y Kiyohara M Kubo et al. (2003) ArticleTitleInsulin-mediated effects of alcohol intake on serum lipid levels in a general population: the Hisayama Study J Clin Epidemiol 56 196–204 Occurrence Handle10.1016/S0895-4356(02)00578-4 Occurrence Handle12654415

    Article  PubMed  Google Scholar 

  9. KS Lee CY Park KH Meng et al. (1998) ArticleTitleThe association of cigarette smoking and alcohol consumption with other cardiovascular risk factors in men from Seoul, Korea Ann Epidemiol 8 31–38 Occurrence Handle1:STN:280:DyaK1c7islWguw%3D%3D Occurrence Handle9465991

    CAS  PubMed  Google Scholar 

  10. K Nanchahal WD Ashton DA Wood (2000) ArticleTitleAlcohol consumption, metabolic cardiovascular risk factors and hypertension in women Int J Epidemiol 29 57–64 Occurrence Handle10.1093/ije/29.1.57 Occurrence Handle1:STN:280:DC%2BD3c3ht1KnsA%3D%3D Occurrence Handle10750604

    Article  CAS  PubMed  Google Scholar 

  11. SG Wannamethee AG Shaper (2003) ArticleTitleAlcohol, body weight, and weight gain in middle-aged men Am J Clin Nutr 77 1312–1317 Occurrence Handle1:CAS:528:DC%2BD3sXntlamt70%3D Occurrence Handle12716687

    CAS  PubMed  Google Scholar 

  12. IF Godsland F Leyva C Walton M Worthington JC Stevenson (1998) ArticleTitleAssociations of smoking, alcohol and physical activity with risk factors for coronary heart disease and diabetes in the first follow-up cohort of the Heart Disease and Diabetes Risk Indicators in a Screened Cohort study (HDDRISC-1) J Intern Med 244 33–41 Occurrence Handle10.1046/j.1365-2796.1998.00312.x Occurrence Handle1:STN:280:DyaK1czmtFCrtQ%3D%3D Occurrence Handle9698022

    Article  CAS  PubMed  Google Scholar 

  13. SG Wannamethee AG Shaper IJ Perry KG Alberti (2002) ArticleTitleAlcohol consumption and the incidence of type II diabetes J Epidemiol Community Health 56 542–548 Occurrence Handle1:STN:280:DC%2BD38zjslKnsQ%3D%3D Occurrence Handle12080164

    CAS  PubMed  Google Scholar 

  14. M McKee A Britton (1998) ArticleTitleThe positive relationship between alcohol and heart disease in eastern Europe: potential physiological mechanisms J R Soc Med 91 402–407 Occurrence Handle1:STN:280:DyaK1M%2FjtlWnsw%3D%3D Occurrence Handle9816353

    CAS  PubMed  Google Scholar 

  15. FD Fuchs LE Chambless AR Folsom et al. (2004) ArticleTitleAssociation between alcoholic beverage consumption and incidence of coronary heart disease in whites and blacks: the Atherosclerosis Risk in Communities Study Am J Epidemiol 160 466–474 Occurrence Handle10.1093/aje/kwh229 Occurrence Handle15321844

    Article  PubMed  Google Scholar 

  16. JM Dorn K Hovey P Muti et al. (2003) ArticleTitleAlcohol drinking patterns differentially affect central adiposity as measured by abdominal height in women and men J Nutr 133 2655–2662 Occurrence Handle1:CAS:528:DC%2BD3sXmt1Sju7s%3D Occurrence Handle12888654

    CAS  PubMed  Google Scholar 

  17. S Stranges T Wu JM Dorn et al. (2004) ArticleTitleRelationship of alcohol drinking pattern to risk of hypertension: a population-based study Hypertension 44 813–819 Occurrence Handle10.1161/01.HYP.0000146537.03103.f2 Occurrence Handle1:CAS:528:DC%2BD2cXpvVGmu70%3D Occurrence Handle15477381

    Article  CAS  PubMed  Google Scholar 

  18. M Russell JR Marshall M Trevisan et al. (1997) ArticleTitleTest-retest reliability of the cognitive lifetime drinking history Am J Epidemiol 146 975–981 Occurrence Handle1:STN:280:DyaK1c%2Fmt1ylug%3D%3D Occurrence Handle9400340

    CAS  PubMed  Google Scholar 

  19. MC Dufour (1999) ArticleTitleWhat is moderate drinking? Defining “drinks” and drinking levels Alcohol Res Health 23 5–14 Occurrence Handle1:STN:280:DC%2BD3czpsVShsw%3D%3D Occurrence Handle10890793

    CAS  PubMed  Google Scholar 

  20. Manual of operations for “Intersalt”: An international cooperative study on the relation of sodium and potassium to blood pressure. In: Meinert CL (ed), Controlled Clinical Trials: Design, Methods and Analysis. 1988: 7s–12s.

  21. The Expert Panel. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143–3421.

    Google Scholar 

  22. InstitutionalAuthorNameAmerican Diabetes Association (2004) ArticleTitleDiagnosis and Classification of Diabetes Mellitus Diabetes Care 27 S5–S10

    Google Scholar 

  23. G Block M Woods A Potosky C Clifford (1990) ArticleTitleValidation of a self-administered diet history questionnaire using multiple diet records J Clin Epidemiol 43 1327–1335 Occurrence Handle10.1016/0895-4356(90)90099-B Occurrence Handle1:STN:280:By6D2szhsF0%3D Occurrence Handle2254769

    Article  CAS  PubMed  Google Scholar 

  24. JF Sallis WL Haskell PD Wood et al. (1985) ArticleTitlePhysical activity assessment methodology in the Five-City Project Am J Epidemiol 121 91–106 Occurrence Handle1:STN:280:BiqD28bkslY%3D Occurrence Handle3964995

    CAS  PubMed  Google Scholar 

  25. IB Puddey V Rakic SB Dimmitt LJ Beilin (1999) ArticleTitleInfluence of pattern of drinking on cardiovascular disease and cardiovascular risk factors – a review Addiction 94 649–663 Occurrence Handle10.1046/j.1360-0443.1999.9456493.x Occurrence Handle1:STN:280:DC%2BD3c%2FivVOksg%3D%3D Occurrence Handle10563030

    Article  CAS  PubMed  Google Scholar 

  26. M Russell ML Cooper MR Frone JW Welte (1991) ArticleTitleAlcohol drinking patterns and blood pressure Am J Public Health 81 452–457 Occurrence Handle1:STN:280:By6C28ngtFM%3D Occurrence Handle2003623

    CAS  PubMed  Google Scholar 

  27. M Trevisan J Dorn K Falkner et al. (2004) ArticleTitleDrinking pattern and risk of non-fatal myocardial infarction: a population-based case–control study Addiction 99 313–22 Occurrence Handle10.1111/j.1360-0443.2003.00630.x Occurrence Handle14982544

    Article  PubMed  Google Scholar 

  28. P McElduff AJ Dobson (1997) ArticleTitleHow much alcohol and how often? Population based case–control study of alcohol consumption and risk of a major coronary event Br Med J 314 1159–1164 Occurrence Handle1:STN:280:ByiB1M7osVw%3D

    CAS  Google Scholar 

  29. M Russell JM Light PJ Gruenewald (2004) ArticleTitleAlcohol consumption and problems: The relevance of drinking pattern Alcohol Clin Exp Res 28 921–930 Occurrence Handle15201635

    PubMed  Google Scholar 

  30. D Goude B Fagerberg J Hulthe (2002) ArticleTitleAlcohol consumption, the metabolic syndrome and insulin resistance in 58-year-old clinically healthy men (AIR study) Clin Sci (Lond) 102 345–352

    Google Scholar 

  31. J Lidfeldt P Nyberg C Nerbrand G Samsioe B Schersten CD Agardh (2003) ArticleTitleSocio-demographic and psychosocial factors are associated with features of the metabolic syndrome. The Women’s Health in the Lund Area (WHILA) study Diabetes Obes Metab 5 106–112 Occurrence Handle10.1046/j.1463-1326.2003.00250.x Occurrence Handle1:STN:280:DC%2BD3s7jslyltw%3D%3D Occurrence Handle12630935

    Article  CAS  PubMed  Google Scholar 

  32. EB Rimm A Klatsky D Grobbee MJ Stampfer (1996) ArticleTitleReview of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits Br Med J 312 731–736 Occurrence Handle1:STN:280:BymC1c%2FnsVQ%3D

    CAS  Google Scholar 

  33. AL Klatsky MA Armstrong GD Friedman (1992) ArticleTitleAlcohol and mortality Ann Intern Med 117 646–654 Occurrence Handle1:STN:280:By2H3M7kvFE%3D Occurrence Handle1530196

    CAS  PubMed  Google Scholar 

  34. MJ Thun R Peto AD Lopez et al. (1997) ArticleTitleAlcohol consumption and mortality among middle-aged and elderly U.S. adults N Engl J Med 337 1705–1714 Occurrence Handle10.1056/NEJM199712113372401 Occurrence Handle1:STN:280:DyaK1c%2FktFyjsw%3D%3D Occurrence Handle9392695

    Article  CAS  PubMed  Google Scholar 

  35. M Maclure (1993) ArticleTitleDemonstration of deductive meta-analysis: ethanol intake and risk of myocardial infarction Epidemiol Rev 15 328–351 Occurrence Handle1:STN:280:ByuB38bhvFA%3D Occurrence Handle8174661

    CAS  PubMed  Google Scholar 

  36. KJ Mukamal KM Conigrave MA Mittleman et al. (2003) ArticleTitleRoles of drinking pattern and type of alcohol consumed in coronary heart disease in men N Engl J Med 348 109–118 Occurrence Handle10.1056/NEJMoa022095 Occurrence Handle12519921

    Article  PubMed  Google Scholar 

  37. K Poikolainen (1998) ArticleTitleIt can be bad for the heart, too-drinking patterns and coronary heart disease Addiction 93 1757–1759 Occurrence Handle10.1046/j.1360-0443.1998.931217571.x Occurrence Handle1:STN:280:DyaK1M7isFCrsg%3D%3D Occurrence Handle9926564

    Article  CAS  PubMed  Google Scholar 

  38. J Rehm R Room K Graham M Monteiro G Gmel CT Sempos (2003) ArticleTitleThe relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: an overview Addiction 98 1209–1228 Occurrence Handle12930209

    PubMed  Google Scholar 

  39. RP Murray JE Connett SL Tyas et al. (2002) ArticleTitleAlcohol volume, drinking pattern, and cardiovascular disease morbidity and mortality: is there a U-shaped function? Am J Epidemiol 155 242–248 Occurrence Handle11821249

    PubMed  Google Scholar 

  40. S Kiechl J Willeit G Rungger G Egger F Oberhollenzer E Bonora (1998) ArticleTitleAlcohol consumption and atherosclerosis: what is the relation? Prospective results from the Bruneck Study Stroke 29 900–907 Occurrence Handle1:STN:280:DyaK1c3lsFKksw%3D%3D Occurrence Handle9596232

    CAS  PubMed  Google Scholar 

  41. AG Shaper G Wannamethee M Walker (1988) ArticleTitleAlcohol and mortality in British men: explaining the U-shaped curve Lancet 2 1267–1273 Occurrence Handle1:STN:280:BiaD2MnkvVU%3D Occurrence Handle2904004

    CAS  PubMed  Google Scholar 

  42. AG Shaper (1990) ArticleTitleAlcohol and mortality: a review of prospective studies Br J Addict 85 837–847 Occurrence Handle1:STN:280:By%2BA2szpvFI%3D Occurrence Handle2204454

    CAS  PubMed  Google Scholar 

  43. K Mukamal EB Rimm (2001) ArticleTitleAlcohol’s effects on the risk for coronary heart disease Alcohol Res Health 25 255–262 Occurrence Handle1:STN:280:DC%2BD387nvVKrtw%3D%3D Occurrence Handle11910702

    CAS  PubMed  Google Scholar 

  44. J Jaccard (1998) Interaction Effects in Factorial Analysis of Variance. sage University Paper series on Quantitative Applications in the Social Sciences Sage Thousand oaks, CA 7–118

    Google Scholar 

  45. InstitutionalAuthorNameUS Department of Agriculture & US Department of Health, Human Services (2005) Nutrition and Your Health: Dietary Guidelines for Americans EditionNumber6 US Government Printing Office Washington, DC

    Google Scholar 

  46. TS Naimi RD Brewer A Mokdad C Denny MK Serdula JS Marks (2003) ArticleTitleBinge drinking among US adults Jama 289 70–75 Occurrence Handle12503979

    PubMed  Google Scholar 

  47. MS Mumenthaler JL Taylor R O’Hara JA Yesavage (1999) ArticleTitleGender differences in moderate drinking effects Alcohol Res Health 23 55–64 Occurrence Handle1:STN:280:DC%2BD3czpsVShsA%3D%3D Occurrence Handle10890798

    CAS  PubMed  Google Scholar 

  48. M Rosell U Faire Particlede ML Hellenius (2003) ArticleTitleLow prevalence of the metabolic syndrome in wine drinkers–is it the alcohol beverage or the lifestyle? Eur J Clin Nutr 57 227–234 Occurrence Handle10.1038/sj.ejcn.1601548 Occurrence Handle1:STN:280:DC%2BD3s%2FmtVOnsQ%3D%3D Occurrence Handle12571653

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Prevention Research Center, Pacific Institute for Research and Evaluation (PIRE), Berkeley, CA, USA

    Amy Z. Fan & Marcia Russell

  2. Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA

    Joan Dorn, Jo L. Freudenheim, Kathy Hovey & Maurizio Trevisan

  3. School of Social Work, University at Buffalo, Buffalo, NY, USA

    Thomas Nochajski

  4. Prevention Research Center, Pacific Institute for Research and Evaluation (PIRE), University Avenue, Suite 450, Berkeley, CA, 94704, USA

    Amy Z. Fan

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  1. Amy Z. Fan
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  2. Marcia Russell
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  3. Joan Dorn
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Correspondence to Amy Z. Fan.

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Fan, A.Z., Russell, M., Dorn, J. et al. Lifetime Alcohol Drinking Pattern is Related to the Prevalence of Metabolic Syndrome. The Western New York Health Study (WNYHS). Eur J Epidemiol 21, 129–138 (2006). https://doi.org/10.1007/s10654-005-5457-y

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