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Pattern ERG in central serous retinopathy

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Abstract

Background

To evaluate the pattern electroretinogram (PERG) in central serous retinopathy.

Methods

In this prospective study, 20 patients with recent onset (<6 weeks) unilateral CSR were studied with the fellow eye acting as control. BCVA, psychophysical parameters, FFA, OCT, flash and pattern ERG were evaluated.

Results

The mean P50 amplitude in the affected eye at presentation was 2.36 ± 0.8 μv compared to 3.24 ± 0.85 μv in the normal eye. At 12 weeks, the mean P50 amplitude in the affected eye was 3.16 ± 0.88 μv compared to 3.63 ± 0.82 μv in the normal eye. The reduction of 27 % in P50 amplitude even after recovery was statistically significant (P < 0.001). A reduction of 19.77 % in the amplitude of N95 wave in the affected eye compared to the normal eye was seen, which was statistically significant (P < 0.001). In the affected eye, there was statistically significant improvement in the psychophysical tests at 12 weeks.

Conclusions

This study reveals that P50 component of the PERG is reduced in cases of CSR, indicating functional disturbance of the macular photoreceptors. A normal flash ERG indicates that pathology is electrophysiologically localised to macula without affecting general retina. Residual deficit in the PERG explains poor quality of vision in spite of normal anatomical apposition and quantitative 6/6 visual acuity.

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Authors and Affiliations

  1. Guru Nanak Eye Centre, Maulana Azad Medical College, Maharaja Ranjeet Singh Marg, New Delhi, 110002, India

    Jawahar Lal Goyal, Basudeb Ghosh, Vishram Sangit, Sushil Kumar, Parul Jain, Vikas Veerwal & Ritu Arora

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  1. Jawahar Lal Goyal
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  2. Basudeb Ghosh
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  3. Vishram Sangit
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  4. Sushil Kumar
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  5. Parul Jain
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  6. Vikas Veerwal
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  7. Ritu Arora
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Corresponding author

Correspondence to Parul Jain.

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Goyal, J.L., Ghosh, B., Sangit, V. et al. Pattern ERG in central serous retinopathy. Doc Ophthalmol 130, 141–147 (2015). https://doi.org/10.1007/s10633-014-9475-5

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  • DOI: https://doi.org/10.1007/s10633-014-9475-5

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