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Is Colonoscopic Screening Necessary for Patients with Gastric Adenoma or Cancer?

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Abstract

Background

Since colorectal adenoma or cancer is commonly associated with gastric adenoma or cancer, early colorectal adenoma detection can affect the survival of gastric adenoma or cancer patients.

Aims

The purpose here was to investigate the colorectal adenoma or cancer prevalence and evaluate the necessity for screening colonoscopy in gastric adenoma or cancer patients.

Patients and methods

From September 2005 through August 2010, 857 patients younger than 70 years who had gastric adenoma or cancer were enrolled. Healthy age- and sex-matched controls were selected from the general screening population. The prevalence and risk of colorectal adenoma or cancer were compared between the participants and the controls.

Results

Data from 416 patients in the gastric neoplasm group (123 with gastric adenoma and 293 with gastric cancer) and 416 healthy control group participants were included in the statistical analysis. The presence of gastric adenoma or cancer was an independent risk factor for colorectal neoplasm (OR = 1.348, 95 % CI = 1.001–1.815). Patients with diffuse type gastric cancer had a lower prevalence of colorectal adenoma or cancer than those with gastric adenoma or intestinal type cancer. In gastric cancer patients younger than 50 years, intestinal type histology was significantly associated with colorectal adenoma or cancer (OR = 3.838, 95 % CI = 1.077–13.677).

Conclusions

The colorectal adenoma or cancer risk was significantly increased in patients with gastric adenoma or cancer. Therefore, screening colonoscopy should be considered for gastric adenoma or cancer patients including young patients, in the case of intestinal type gastric cancer.

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Acknowledgments

There have been no sources of support, including pharmaceutical and industry support.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, 516 Gojan-dong, Danwon-gu, Ansan, Gyeonggi-do, 425-707, Korea

    Seung Young Kim, Sung Woo Jung, Jong Jin Hyun, Ja Seol Koo, Rok Seon Choung, Hyung Joon Yim, Sang Woo Lee & Jai Hyun Choi

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  1. Seung Young Kim
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  2. Sung Woo Jung
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  3. Jong Jin Hyun
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Correspondence to Sung Woo Jung.

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Kim, S.Y., Jung, S.W., Hyun, J.J. et al. Is Colonoscopic Screening Necessary for Patients with Gastric Adenoma or Cancer?. Dig Dis Sci 58, 3263–3269 (2013). https://doi.org/10.1007/s10620-013-2824-5

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  • DOI: https://doi.org/10.1007/s10620-013-2824-5

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