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Risk Factors for Hypoxemia During Ambulatory Gastrointestinal Endoscopy in ASA I–II Patients

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Abstract

Background Most studies identify the American Society of Anesthesiology (ASA) classification as the most significant risk factor for hypoxemia. The risk factors operative within ASA I and II patients are not well defined. Therefore, we analyzed prospectively collected data to identify the risk factors of hypoxemia in such patients. Methods A combination of a narcotic and benzodiazepine was used for sedation and oxygen was supplemented if hypoxemia (oxygen saturation ≤90%) developed. Univariate and multivariate analyses were performed and correlations estimated for predetermined clinical variables. Results 40 of 79 patients (51%) developed hypoxemia, which occurred more frequently in the obese (71%; 10/14) than the nonobese (46%; 30/65) group (P = 0.08). On multivariate analysis, the odds ratios (OR) and 95% confidence intervals (CI) for developing hypoxemia were age ≥ 60 years 4.5 (1.4–14.3) P = 0.01, and incremental 25-mg doses of meperidine 2.6 (1.02–6.6) P = 0.04. Body mass index (BMI) significantly correlated with the number of hypoxemic episodes (rho 0.26, 95% CI 0.04–0.48, P = 0.02). Conclusion In ASA I and II patients, BMI significantly correlated with the number of hypoxemic episodes, whereas age ≥ 60 years and meperidine dose were significant risk factors for hypoxemia.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A 30, Cleveland, OH, 44195, USA

    Mohammed A. Qadeer, John A. Dumot & John J. Vargo

  2. Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA

    A. Rocio Lopez

Authors
  1. Mohammed A. Qadeer
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  2. A. Rocio Lopez
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  3. John A. Dumot
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  4. John J. Vargo
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Correspondence to John J. Vargo.

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Qadeer, M.A., Rocio Lopez, A., Dumot, J.A. et al. Risk Factors for Hypoxemia During Ambulatory Gastrointestinal Endoscopy in ASA I–II Patients. Dig Dis Sci 54, 1035–1040 (2009). https://doi.org/10.1007/s10620-008-0452-2

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  • DOI: https://doi.org/10.1007/s10620-008-0452-2

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