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Progress of Study on the Relationship Between Mediators of Inflammation and Apoptosis in Acute Pancreatitis

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Abstract

As an important pathological feature of acute pancreatitis, apoptosis may occur in multiple organs and relate directly to the progression of disease. It is mainly controlled by the apoptosis gene and also influenced by inflammatory mediators. We summarize here the roles of the main inflammatory mediators (e.g., NO, TNF-α, TGF-β1, IL-10, NF-κB) during the pathologic process of acute pancreatitis.

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Acknowledgments

This work was supported by technological foundation projects for traditional Chinese medical science of Zhejiang province (Nos. 2003C130 and 2004C142), a foundation project for medical science and technology of Zhejiang province (No. 2003B134), a grave foundation project for technological and development of Hangzhou (No. 2003123B19), an intensive foundation project for technology of Hangzhou (No. 2004Z006), a foundation project for medical science and technology of Hangzhou (No.2003A004), and a foundation project for technology of Hangzhou (No. 2005224).

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  1. Department of General Surgery, Hangzhou First People’s Hospital, Hangzhou, 310006, Zhejiang Province, China

    Xi-Ping Zhang

  2. Zhejiang College of Traditional Chinese Medical, Hangzhou, 310053, Zhejiang Province, China

    Qian Lin

  3. Department of Digest, Hangzhou First People’s Hospital, Hangzhou, 310006, Zhejiang Province, China

    Yi-Feng Zhou

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Correspondence to Xi-Ping Zhang.

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We claim that this review is original, and we do not have any financial interest in a company or its competitor, and that all authors meet the criteria for authorship.

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Zhang, XP., Lin, Q. & Zhou, YF. Progress of Study on the Relationship Between Mediators of Inflammation and Apoptosis in Acute Pancreatitis. Dig Dis Sci 52, 1199–1205 (2007). https://doi.org/10.1007/s10620-006-9388-6

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