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Hyperplastic Polyps of the Gastric Antrum in Patients with Gastrointestinal Blood Loss

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Abstract

The significance of hyperplastic polyps of the gastric antrum in anemic patients with suspected gastrointestinal bleeding has not been determined. The aim of this study is to evaluate the prevalence and prognosis of such polyps in this patient group. Clinical records of patients referred to our endoscopy lab from November 1999 to February 2003 for the evaluation of iron deficiency anemia or suspected gastrointestinal bleeding were reviewed. There were 987 patients. Fourteen patients (1.4%) had hyperplastic polyps in the gastric antrum. Five of the patients reported melena, but the rest were asymptomatic. Multiple antral polyps were present in seven cases. The largest polyp measured 5.0 cm. Helicobacter pylori infection was present in one patient. All patients were anemic and nine had documented iron deficiency. No follow-up information was available in four patients. Hyperplastic polyps of the gastric antrum are a rare but significant cause of gastrointestinal blood loss in older patients. Removal of the polyps using endoscopic or surgical methods may be required for resolution of the blood loss along with iron supplementation. Gastroenterologists should be aware that hyperplastic polyps of the gastric antrum might result in gastrointestinal blood loss and iron deficiency anemia.

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References

  1. Rosch W (1980) Epidemiology, pathogenesis, diagnosis and treatment of benign gastric tumours. Front Gastrointest Res 6:167–184

    PubMed  CAS  Google Scholar 

  2. Zea-Iriarte WL, Sekine I, Itsuno M, et al. (1996) Carcinoma in gastric hyperplastic polyps. A phenotypic study. Dig Dis Sci 41:377–386

    Article  PubMed  CAS  Google Scholar 

  3. Debongnie JC (1999) Gastric polyps. Acta Gastroenterol Belg 62:187–189

    PubMed  CAS  Google Scholar 

  4. Veereman Wauters G, Ferrell L, Ostroff JW, et al. (1990) Hyperplastic gastric polyps associated with persistent Helicobacter pylori infection and active gastritis. Am J Gastroenterol 85:1395–1397

    PubMed  CAS  Google Scholar 

  5. Mocek FW, Ward WW Jr, Wolfson SE, et al. (1994) Elimination of recurrent hyperplastic polyps by eradication of Helicobacter pylori. Ann Intern Med 120:1007–1008

    PubMed  CAS  Google Scholar 

  6. Suzuki S, Ohkusa T, Shimoi K, et al. (1997) Disappearance of multiple hyperplastic polyps after the eradication of Helicobacter pylori. Gastrointest Endosc 46:566–568

    Article  PubMed  CAS  Google Scholar 

  7. Nakajima A, Matsuhashi N, Yazaki Y, et al. (2000) Details of hyperplastic polyps of the stomach shrinking after anti-Helicobacter pylori therapy. J Gastroenterol 35:372–375

    Article  PubMed  CAS  Google Scholar 

  8. Daibo M, Itabashi M, Hirota T (1987) Malignant transformation of gastric hyperplastic polyps. Am J Gastroenterol 82:1016–1025

    PubMed  CAS  Google Scholar 

  9. Hizawa K, Fuchigami T, Iida M, et al. (1995) Possible neoplastic transformation within gastric hyperplastic polyp. Application of endoscopic polypectomy. Surg Endosc 9:714–718

    PubMed  CAS  Google Scholar 

  10. Ginsberg GG, Al-Kawas FH, Fleischer DE, et al. (1996) Gastric polyps: relationship of size and histology to cancer risk. Am J Gastroenterol 91:714–717

    PubMed  CAS  Google Scholar 

  11. Dean PG, Davis PM, Nascimento AG, et al. (1998) Hyperplastic gastric polyp causing progressive gastric outlet obstruction. Mayo Clin Proc 73:964–967

    PubMed  CAS  Google Scholar 

  12. Siu WT, Leong HT, Li MK (1997) Laparoscopic resection of bleeding gastric polyps. Surg Endosc 11:283–284

    Article  PubMed  CAS  Google Scholar 

  13. Rockey DC (1999) Occult gastrointestinal bleeding. N Engl J Med 341:38–46

    Article  PubMed  CAS  Google Scholar 

  14. Zuckerman GR, Prakash C, Askin MP, et al. (2000) AGA technical review on the evaluation and management of occult and obscure gastrointestinal bleeding. Gastroenterology 118:201–221

    Article  PubMed  CAS  Google Scholar 

  15. Vittal SB (1975) Endoscopic polypectomy of a symptomatic antral polyp. Am J Gastroenterol 64:55–58

    PubMed  CAS  Google Scholar 

  16. Geller A, Gostout CJ, Balm RK (1996) Development of hyperplastic polyps following laser therapy for watermelon stomach. Gastrointest Endosc 43:54–56

    PubMed  CAS  Google Scholar 

  17. Amaro R, Neff GW, Karnam US, et al. (2002) Acquired hyperplastic gastric polyps in solid organ transplant patients. Am J Gastroenterol 97:2220–2224

    Article  PubMed  Google Scholar 

  18. Alper M, Akcan Y, Belenli O (2003) Large pedunculated antral hyperplastic gastric polyp traversed the bulbus causing outlet obstruction and iron deficiency anemia: endoscopic removal. World J Gastroenterol 9:633–634

    PubMed  Google Scholar 

  19. Stolte M, Sticht T, Eidt S, et al. (1994) Frequency, location, and age and sex distribution of various types of gastric polyp. Endoscopy 26:659–665

    Article  PubMed  CAS  Google Scholar 

  20. Payen JL, Cales P (1991) Gastric modifications in cirrhosis. Gastroenterol Clin Biol 15:285–295

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Mayo Clinic, 4500 S. Pablo Road, Jacksonville, Florida, 32224, USA

    Mohammad Al-Haddad, Eric M. Ward, Ernest P. Bouras & Massimo Raimondo

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  1. Mohammad Al-Haddad
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  2. Eric M. Ward
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  3. Ernest P. Bouras
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  4. Massimo Raimondo
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Correspondence to Massimo Raimondo.

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Al-Haddad, M., Ward, E.M., Bouras, E.P. et al. Hyperplastic Polyps of the Gastric Antrum in Patients with Gastrointestinal Blood Loss. Dig Dis Sci 52, 105–109 (2007). https://doi.org/10.1007/s10620-006-9182-5

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  • DOI: https://doi.org/10.1007/s10620-006-9182-5

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