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Extremely Elevated CA19-9 in Acute Cholangitis

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Abstract

A 68-year-old women was admitted with the chief complaints of epigastralgia with radiation to the back and jaundice. Fever and chills were also noted. The laboratory data showed alkaline phosphatase, 245 U/L (normal range: 28–94); Direct Bilirubin, 5.29 mg% (0–0.4); Total Bilirubin, 8.4 mg% (0.2–1.4). Surprisingly, the serum CA19-9 was 5673.8 U/ml (normal value: <37). Abdominal sonography showed dilated common hepatic duct. MRCP demonstrated diffuse biliary tree dilatation with a very low signal intensity in distal common bile duct. Surgical intervention reveled a black stone at distal common bile duct and was successfully retrieved. After operation, the CA19-9 fell to 63.1 u/ml two weeks later and returned to normal (10.4 U/ml) one month later.

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Authors and Affiliations

  1. Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung, 123, Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan

    Shyr-Ming Sheen-Chen, Cheuk-Kwan Sun & Yei-Wei Liu

  2. Department of Pathology, Chang Gung Memorial Hospital, Kaohsiung, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Hock-Liew Eng

  3. Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Kaohsiung, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Sheung-Fat Ko

  4. Department of Gastroenterology, Chang Gung Memorial Hospital, Kaohsiung, College of Medicine, Chang Gung University, Taoyuan, Taiwan

    Chung-Huang Kuo

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  1. Shyr-Ming Sheen-Chen
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  2. Cheuk-Kwan Sun
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  3. Yei-Wei Liu
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  4. Hock-Liew Eng
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  5. Sheung-Fat Ko
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  6. Chung-Huang Kuo
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Correspondence to Shyr-Ming Sheen-Chen.

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Sheen-Chen, SM., Sun, CK., Liu, YW. et al. Extremely Elevated CA19-9 in Acute Cholangitis. Dig Dis Sci 52, 3140–3142 (2007). https://doi.org/10.1007/s10620-006-9164-7

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  • DOI: https://doi.org/10.1007/s10620-006-9164-7

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