Skip to main content
SpringerLink
Log in

New Benzofuran Lignans from Nepeta multifida

  • Published:
Chemistry of Natural Compounds Aims and scope

The new benzofuran lignans nepetamultin A (1) and B (2) were isolated from flowers of Nepeta multifida L. [Schizonepeta multifida (L.) Briq.; Lamiaceae]. UV and NMR spectroscopic and mass spectrometric data indicated 1 was the 9′9′′′-di-O-methyl ester of schizotenuin A; 2, the 9′-O-methyl ester of schizotenuin C1. Biological studies revealed that 1 and 2 possessed antioxidant and antihyaluronidase activity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. S. M. Batorova, G. P. Yakovlev, and T. A. Aseeva, Handbook of Medicinal Plants of Traditional Tibetan Medicine [in Russian], Nauka, Novosibirsk, 2003, 291 pp.

  2. Ya. G. Razuvaeva, D. V. Kharzheev, A. A. Toropova, and D. N. Olennikov, Vopr. Biol., Med. Farm. Khim., 21, 5 (2018).

  3. A. V. Rumak and V. A. Khan, Chem. Nat. Compd., 25, 254 (1989).

    Article  Google Scholar 

  4. E. A. Korolyuk and A. V. Tkachev, Khim. Rastit. Syr′ya, No. 1, 53 (2002).

  5. S. Shatar and S. Altanctetceq, J. Essent. Oil-Bear. Plants, 6, 214 (2003).

    Article  CAS  Google Scholar 

  6. D. N. Olennikov, N. K. Chirikova, E. Kim, S. W. Kim, and I. S. Zul′fugarov, Chem. Nat. Compd., 54, 860 (2018).

  7. N. K. Chirikova and D. N. Olennikov, Chem. Nat. Compd., 54, 572 (2018).

    Article  CAS  Google Scholar 

  8. D. N. Olennikov, Plants, 9, 1555 (2020).

    Article  CAS  Google Scholar 

  9. M. Matsuta, R. Kanita, Y. Saito, and A. Yamashita, Nat. Med. (Tokyo, Jpn.), 50, 204 (1996).

  10. H. Huang, H.-D. Sun, M.-S. Wang, and S.-X. Zhao, J. Nat. Prod., 59, 1079 (1996).

    Article  CAS  Google Scholar 

  11. S. Maeda, H. Masuda, and T. Tokoroyama, Chem. Pharm. Bull., 42, 2500 (1994).

    Article  CAS  Google Scholar 

  12. D. N. Olennikov, L. M. Tankhaeva, and V. V. Partilkhaev, Chem. Nat. Compd., 48, 114 (2012).

    Article  CAS  Google Scholar 

  13. V. M. Malikov and M. P. Yuldashev, Chem. Nat. Compd., 38, 358 (2002).

    Article  CAS  Google Scholar 

  14. F. Moussaoui, A. Zellagui, N. Segueni, A. Touil, and S. Rhouati, Rec. Nat. Prod., 4, 91 (2010).

    CAS  Google Scholar 

  15. M. Mizuno, M. Kato, M. Iinuma, T. Tanaka, A. Kimura, H. Ohashi, and H. Sakai, Phytochemistry, 26, 2418 (1987).

    Article  CAS  Google Scholar 

  16. D. N. Olennikov, L. M. Tankhaeva, V. V. Partilkhaev, and A. V. Rokhin, Braz. J. Pharmacogn., 22, 490 (2012).

    Article  CAS  Google Scholar 

  17. Y. Lu and L. Y. Foo, Food Chem., 65, 1 (1999).

    Article  CAS  Google Scholar 

  18. I. K. Lee, M. A. Kim, S. Y. Lee, J. K. Hong, J. H. Lee, and K. R. Lee, Nat. Prod. Sci., 14, 100 (2008).

    Article  Google Scholar 

  19. X.-H. Huang, J. Chen, X.-Q. Xu, W.-T. Zhang, and C.-C. Zhao, Chem. Nat. Compd., 52, 1005 (2016).

    Article  CAS  Google Scholar 

  20. J.-H. Shao, X.-Q. Ge, T. Chen, and R. Zhao, Chem. Nat. Compd., 51, 336 (2015).

    Article  CAS  Google Scholar 

  21. A. Sharma, R. Cooper, G. Bhardwaj, and D. S. Cannoo, J. Ethnopharmacol., 268, 113679 (2021).

    Article  CAS  Google Scholar 

  22. T. Murata, M. Watahiki, Y. Tanaka, T. Miyase, and F. Yoshizaki, Chem. Pharm. Bull., 58, 394 (2010).

    Article  CAS  Google Scholar 

  23. H. Kakegawa, H. Matsumoto, and T. Satoh, Chem. Pharm. Bull., 40, 1439 (1992).

    Article  CAS  Google Scholar 

  24. D. N. Olennikov, A. G. Vasilieva, and N. K. Chirikova, Pharmaceuticals, 13, 262 (2020).

    Article  CAS  Google Scholar 

  25. D. C. Tabor, S. A. Evans, and W. R. Kenan, Synth. Commun., 12, 855 (1982).

    Article  CAS  Google Scholar 

  26. T. Murata, K. Sasaki, K. Sato, F. Yoshizaki, H. Yamada, H. Mutoh, K. Umehara, T. Miyase, T. Warashina, H. Aoshima, H. Tabata, and K. Matsubara, J. Nat. Prod., 72, 1379 (2009).

    Article  CAS  Google Scholar 

  27. D. N. Olennikov, N. K. Chirikova, A. G. Vasilieva, and I. A. Fedorov, Antioxidants, 9, 526 (2020).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

The studies were supported by the Ministry of Education and Science of the Russian Federation (Project No. 121030100227-7).

Author information

Authors and Affiliations

  1. Institute of General and Experimental Biology, Siberian Branch, Russian Academy of Sciences, 6 Sakh’yanovoi St., Ulan-Ude, 670047, Russia

    D. N. Olennikov

Authors
  1. D. N. Olennikov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. N. Olennikov.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2021, pp. 703–706.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Olennikov, D.N. New Benzofuran Lignans from Nepeta multifida. Chem Nat Compd 57, 818–822 (2021). https://doi.org/10.1007/s10600-021-03488-7

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-021-03488-7

Keywords

Search

Navigation