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Two New Furan-2-Carboxylic Derivatives from the Leaves of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activities

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Chemistry of Natural Compounds Aims and scope

Two new furan-2-carboxylic derivatives (1 and 2), together with three known compounds (3–5), were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-TMV activities. The results showed that compounds 1 and 2 exhibited high anti-TMV activity with inhibition rates of 33.2 and 30.8%. These rates are close to that of positive control.

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Acknowledgment

This project was supported financially by the Foundation of Yunnan Tobacco Industry Co., Ltd. (2020JC04, 2018JC07), the Founation of China Tobacco Company (No. 110201901016), the high tech projects of Yunnan Province (2017ZEO27), and the National Natural Science Foundation of China (No. 31860100).

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Authors and Affiliations

  1. School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, 650500, Kunming, P. R. China

    Xue Wang, Li-Jia Huang, Meng-Jie Liang, Guang-Yu Yang, Liang Deng & Qian Gao

  2. Key Laboratory of Tobacco Chemistry of Yunnan Province, China Tobacco Yunnan Industrial Co., Ltd, 650231, Kunming, P. R. China

    Xue Wang, Li-Jia Huang, Meng-Jie Liang, Yin-Ke Li, Wan-Li Zeng, Hai-Ying Xiang, Jing Li, Xin Liu, Qi-Li Mi, Ya-Dong Guo & Qian Gao

  3. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, 650031, Kunming, P. R. China

    Guang-Yu Yang

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  1. Xue Wang
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  2. Li-Jia Huang
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  3. Meng-Jie Liang
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  8. Xin Liu
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  12. Liang Deng
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Corresponding authors

Correspondence to Liang Deng or Qian Gao.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2020, pp. 726–729.

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Wang, X., Huang, LJ., Liang, MJ. et al. Two New Furan-2-Carboxylic Derivatives from the Leaves of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activities. Chem Nat Compd 56, 848–851 (2020). https://doi.org/10.1007/s10600-020-03167-z

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  • DOI: https://doi.org/10.1007/s10600-020-03167-z

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