A new bisepoxylignan glucoside, named phillygenin 4-O-(6′′-O-acetyl)-β-D-glucopyranoside (1), along with two known compounds, 3β-acetoxyurs-11-en-28,13-olide (2) and epipinoresinol-4-O-β-D-glusoside (3), was isolated from the leaves of Forsythia suspensa. The structure was established on the basis of spectroscopic data and chemical evidence.
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References
Q. Zhang, C. H. Jia, H. Y. Xu, Y. F. Wang, M. L. Zhang, C. H. Huo, Q. W. Shi, and S. H. Yu, Mini-Rev. Org. Chem., 9, 303 (2012).
W. Y. Kang, J. M. Wang, and L. Zhang, Zhongguo Zhongyao Zazhi, 35, 1156 (2010).
H. L. Xue and W. J. Wang, Shizhen Guoyiguoyao, 20, 1149 (2009).
G. X. Hou and J. X. Yang, J. Henan Univ. (Nat. Sci.), 40, 504 (2010).
Q. X. Lei, L. M. Zhao, X. Yan, Q. Zhang, B. Shan, Y. M. Gen, and B. E. Shan, Cancer Res. Prev. Treat., 39, 394 (2012).
J. Jiao, Q. Y. Gai, M. Luo, W. Wang, C. B. Gu, C. J. Zhao, Y. G. Zu, F. Y. Wei, and Y. J. Fu, Food Res. Inter., 53, 857 (2013).
Y. Ge, Y. Z. Wang, P. P. Chen, Y. F. Wang, C. C. Hou, Y. B. Wu, M. L. Zhang, L. G. Li, C. H. Huo, Q. W. Shi, and H. X. Gao, J. Agric. Food Chem., 64, 125 (2016).
Q. Zhang, Z. Lu, X. Li, Y. Zheng, D. G. Yao, Y. C. Gu, C. H. Huo, and B. Cong, Chem. Nat. Compd., 51, 178 (2015).
S. Kitagawa, S. Nishibe, R. Benecke, and H. Thieme, Chem. Pharm. Bull., 36, 3667 (1988).
S. Kitagawa, S. Hisada, and S. Nishibe, Phytochemistry, 23, 1635 (1988).
M. L. Tan, Y. Wang, L. G. Zhou, and W. B. Jiang, Nat. Prod. Res. Dev., 19, 232 (2007).
M. Chiba, S. Hisada, S. Nishibe, and H. Thieme, Phytochemistry, 19, 335 (1980).
F. Zhang, M. B. Zhao, J. Li, and P. F. Tu, Chin. Trad. Herb. Drugs, 44, 1529 (2013).
M. Chiba, S. Hisada, and S. Nishibe, Chem. Pharm. Bull., 25, 3435 (1977).
Acknowledgment
This work was supported by the Natural Science Foundation of Hebei Province, China (H2015206113) and Department of Education, Hebei Province (ZD2018088).
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2018, pp. 883–885.
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Wang, Y., Zhou, Q., Shi, N. et al. A New Bisepoxylignan Glucoside from the Leaves of Forsythia suspensa. Chem Nat Compd 54, 1038–1040 (2018). https://doi.org/10.1007/s10600-018-2549-y
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DOI: https://doi.org/10.1007/s10600-018-2549-y