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Synthesis and Antioxidant Activity of Myrtanylthiotriazoles

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Chemistry of Natural Compounds Aims and scope

Thio-derivatives of triazole-substituted myrtanols were synthesized in 78–95% yields and were demonstrated to have membrane-protective and antioxidant properties based on their ability to inhibit H2O2-induced hemolysis of erythrocytes and LPO processes in brain lipids (in vitro).

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Acknowledgment

The work was supported financially in part by the RFBR (Project 16-53-00171 Bel_a) using equipment at the Khimiya Center for Collective Use, Inst. Chem., Komi SC, UB, RAS.

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Authors and Affiliations

  1. Institute of Chemistry, Komi Scientific Center, Ural Branch, Russian Academy of Sciences, 48 Pervomaiskaya, Syktyvkar, 167982, Russia

    Yu. V. Gyrdymova, M. Ya. Demakova, D. V. Sudarikov, L. L. Frolova, S. A. Rubtsova & A. V. Kuchin

  2. Institute of Biology, Komi Scientific Center, 28 Kommunisticheskaya, Syktyvkar, 167982, Russia

    O. G. Shevchenko

Authors
  1. Yu. V. Gyrdymova
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  2. M. Ya. Demakova
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  3. O. G. Shevchenko
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  4. D. V. Sudarikov
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  5. L. L. Frolova
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  6. S. A. Rubtsova
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  7. A. V. Kuchin
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Corresponding author

Correspondence to D. V. Sudarikov.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2017, pp. 762–766.

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Gyrdymova, Y.V., Demakova, M.Y., Shevchenko, O.G. et al. Synthesis and Antioxidant Activity of Myrtanylthiotriazoles. Chem Nat Compd 53, 895–900 (2017). https://doi.org/10.1007/s10600-017-2150-9

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  • DOI: https://doi.org/10.1007/s10600-017-2150-9

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