Two new isoquinoline alkaloids, fistulaquinolines A and B (1 and 2), were isolated from the barks of Cassia fistula. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that the two compounds showed weak anti-TMV activity with inhibition rates of 18.9 and 22.6%.
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Acknowledgment
This project was supported by the National Natural Science Foundation of China (Nos. 21302164, 31460144, and 21562044) and the Applied Fundamental Foundation of Yunnan Province (No. 2013FB097).
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2017, pp. 431–433.
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Zhou, L., Liu, LX., Yang, GR. et al. Two New Isoquinoline Alkaloids from the Barks of Cassia fistula and Their Anti-Tobacco Mosaic Virus Activity. Chem Nat Compd 53, 508–511 (2017). https://doi.org/10.1007/s10600-017-2033-0
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DOI: https://doi.org/10.1007/s10600-017-2033-0