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Two New Flavones from Hypericum chinense and Their Anti-Tobacco Mosaic Virus Activity

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Chemistry of Natural Compounds Aims and scope

Two new flavones, 6,4′-dimethoxy-8-formylflavone (1) and 6,7-dimethoxy-8-acetyl-4′-hydroxyflavone (2), together with five known flavones (3–7), were isolated from the leaves and stems of Hypericum chinense. The structure of 1–7 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1, 2, 6, and 7 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 shows high anti-TMV activity with an inhibition rate of 31.4%, which is close to that of the positive control.

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Acknowledgment

This research was supported by the National Natural Science Foundation of China (No. 21362044), the Excellent Scientific and Technological Team of Yunnan High School (2010CI08), and the Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team (2011HC008).

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Authors and Affiliations

  1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, 650031, Kunming, P. R. China

    Bin Zhou, Yinke Li, Yanqing Ye, Xuemei Gao & Qiufen Hu

  2. College of Resource and Environment, Yuxi Normal University, 653100, Yuxi, P. R. China

    Yinke Li, Xianxue Wu & Ming Li

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  1. Bin Zhou
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  2. Yinke Li
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  3. Xianxue Wu
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  4. Ming Li
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  5. Yanqing Ye
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  6. Xuemei Gao
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  7. Qiufen Hu
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Correspondence to Qiufen Hu.

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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2015, pp. 722–724.

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Zhou, B., Li, Y., Wu, X. et al. Two New Flavones from Hypericum chinense and Their Anti-Tobacco Mosaic Virus Activity. Chem Nat Compd 51, 840–843 (2015). https://doi.org/10.1007/s10600-015-1429-y

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  • DOI: https://doi.org/10.1007/s10600-015-1429-y

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