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Two New Polyketides from Mangrove Endophytic Fungus Dothiorella sp.

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Chemistry of Natural Compounds Aims and scope

Two new polyketides, named dothiorelones F (2) and I (3), as well as three known analogues (dothiorelones E (1), G (4), and H (5)) have been isolated from the mangrove endophytic fungus Dothiorella sp. Their structures were elucidated on the basis of NMR data and mass spectrometry. Dothiorelones F (2) and G (4) showed significant cytotoxicity against Raji cancer cell line with IC50 values 2 μg/mL.

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Acknowledgment

This work was supported by the Natural Science Foundation of Fujian (2012J05058), Doctor Foundation of Jimei University (ZQ2011004), and Li Shangda Subject Foundation of Jimei University (C2012006).

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Authors and Affiliations

  1. Bioengineering College, Jimei University, 361021, Xiamen, Fujian, P. R. China

    Xi-Ping Du & Wen-Jin Su

  2. Key Laboratory of Systemic Utilization and in-depth Processing of Economic Seaweed, Xiamen Southern Ocean Technology Center of China, 361021, Xiamen, Fujian Province, P. R. China

    Xi-Ping Du & Wen-Jin Su

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  1. Xi-Ping Du
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  2. Wen-Jin Su
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Correspondence to Wen-Jin Su.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2014, pp. 193–194.

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Du, XP., Su, WJ. Two New Polyketides from Mangrove Endophytic Fungus Dothiorella sp.. Chem Nat Compd 50, 214–216 (2014). https://doi.org/10.1007/s10600-014-0915-y

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  • DOI: https://doi.org/10.1007/s10600-014-0915-y

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