A new flavonoid kaempferol-7,8-diglucoside was isolated for the first time along with two known flavonoid compounds, kaempferol and quercetin, from the methanol extract of Farsetia aegyptia Turra by chromatographic techniques. Two coumarin compounds were isolated and identified from the plant extract. The plant extract contains phenol, catechin, p-hydroxybenzoic acid, gallic acid, pyrogallic acid, p-coumaric acid, and coumarin compounds, which were identified by authentic samples using HPLC. The new compound and alcoholic extract of the plant were evaluated against some bacterial and fungal strains. They showed maximum inhibition against Klebsiella pneumonia. Moderate effects were observed to Aspergillus niger, while the extract did not show activity against Candida albicans.
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Acknowledgment
The authors are grateful to the Chemistry Department, University of Aberdeen, Scotland, UK, for providing the facilities for instrumental analysis.
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2013, pp. 370–373.
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Atta, E.M., Hashem, A.I. & Eman, R.ES. A novel flavonoid compound from Farsetia aegyptia and its antimicrobial activity. Chem Nat Compd 49, 432–436 (2013). https://doi.org/10.1007/s10600-013-0631-z
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DOI: https://doi.org/10.1007/s10600-013-0631-z