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Radical scavenging activity of decalpoline, a novel compound characterized from Decalepis hamiltonii

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Chemistry of Natural Compounds Aims and scope

The ethanol extract of Decalepis hamiltonii roots was subjected to antioxidant activity-guided fractionation by repeated silica gel column chromatography to get a pure antioxidant compound which was subjected to extensive analysis by UV, IR, LC-MS, and 2D HMQC NMR. The spectral data of the isolated compound was analyzed, and its structure was elucidated as decalpoline, a novel antioxidant compound not reported so far. Decalpoline exhibited multiple antioxidant properties like DPPH scavenging activity, superoxide radical scavenging activity, lipid peroxidation inhibitory activity, metal chelating and total reducing activity.

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Authors and Affiliations

  1. Department of Biochemistry and Nutrition, Defence Food Research Laboratory, Siddarthanagar, Mysore, 570011, India

    S. Naveen & K. Farhath

  2. Department of Biotechnology, Defence Research Laboratory, Post Bag No. 2, Solmara, Tezpur, 784001, India

    R. S. Policegoudra

  3. Department of Fruit and Vegetable Technology, Central Food Technological Research Institute, Mysore, 570 020, India

    S. M. Aradhya

  4. Department of Plantation Products, Spices and Flavour Technology, Central Food Technological Research Institute, Mysore, 570 020, India

    L. J. Rao

Authors
  1. S. Naveen
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  2. R. S. Policegoudra
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  3. S. M. Aradhya
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  4. L. J. Rao
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  5. K. Farhath
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Corresponding author

Correspondence to K. Farhath.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2012, pp. 205–209.

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Naveen, S., Policegoudra, R.S., Aradhya, S.M. et al. Radical scavenging activity of decalpoline, a novel compound characterized from Decalepis hamiltonii . Chem Nat Compd 48, 225–230 (2012). https://doi.org/10.1007/s10600-012-0210-8

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  • DOI: https://doi.org/10.1007/s10600-012-0210-8

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