A new taxane, 13-oxobaccatin III (2), and five known taxanes, 10-deacetyl-13-oxobaccatin III (1), baccatin III (3), 7-epi-10-deacetyltaxol (4), 19-debenzoyl-19-acetyltaxinine M (5), and 5a-decinnamoyltaxagifine (6), were isolated from the leaves of the Japanese yew, Taxus cuspidate. Their structures were established on the basis of the analysis of their spectral data.
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Acknowledgment
The work reported in this paper was financially supported by the Scientific Research Foundation for Returning Overseas Chinese Scholars of Hebei Province and the Scientific Research Foundation of Hebei Province (08B032) (QWS). We also appreciate the Syngenta PhD studentship awarded to Manli Zhang in Prof. Qingwen Shi’ s group (2008-Hebei Medical University-Syngenta-02).
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Published in Khimiya Prirodnykh Soedinenii, No. 1, pp. 49–52, January–February, 2010.
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Zhang, M., Lu, X., Zhang, J. et al. Taxanes from the leaves of Taxus cuspidata . Chem Nat Compd 46, 53–58 (2010). https://doi.org/10.1007/s10600-010-9523-7
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DOI: https://doi.org/10.1007/s10600-010-9523-7