2,3,6-Tribromo-4,5-dihydroxybenzyl ethyl ether (1), a new bromophenol, was isolated from the ethanol extract of marine red alga Symphyocladia latiuscula, with a known compound, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether (2). Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1 and 2-dimensional NMR techniques. Compounds 1 and 2 showed inhibitory activity against Staphyloccocus aureus with IC50 102 and 50 μg/mL, respectively.
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This work was supported by 863 Hi-Tech Research and Development Program of China (Grant 2007AA09Z443).
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Published in Khimiya Prirodnykh Soedinenii, No. 6, pp. 680–681, November–December, 2009.
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Xu, X., Song, F., Fan, X. et al. A novel bromophenol from marine red alga Symphyocladia latiuscula . Chem Nat Compd 45, 811–813 (2009). https://doi.org/10.1007/s10600-010-9501-0
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DOI: https://doi.org/10.1007/s10600-010-9501-0