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Synthesis of lupane and 19β,28-epoxy-18α-oleanane 2,3-seco-derivatives based on betulin

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Chemistry of Natural Compounds Aims and scope

The α-hydroxyoximes of methyl betulonate and allobetulone were synthesized. Beckmann fragmentation of them produced the lupane and 19β,28-epoxy-18α-oleanane 2,3-seco-derivatives.

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Acknowledgment

The work was supported financially by the RFBR Grant No. 08-03-00265a.

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Authors and Affiliations

  1. Institute of Chemical Engineering, Ural Branch, Russian Academy of Sciences, 614013, Perm′, ul. Koroleva, 3, Russia

    I. A. Tolmacheva, A. V. Nazarov, O. A. Maiorova & V. V. Grishko

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  1. I. A. Tolmacheva
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  2. A. V. Nazarov
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  3. O. A. Maiorova
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  4. V. V. Grishko
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Corresponding author

Correspondence to V. V. Grishko.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 491–494, September-October, 2008. Original article submitted July 4, 2008.

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Tolmacheva, I.A., Nazarov, A.V., Maiorova, O.A. et al. Synthesis of lupane and 19β,28-epoxy-18α-oleanane 2,3-seco-derivatives based on betulin. Chem Nat Compd 44, 606–611 (2008). https://doi.org/10.1007/s10600-008-9135-7

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  • DOI: https://doi.org/10.1007/s10600-008-9135-7

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