Abstract
The Pictet-Spengler reaction involving β-phenyltryptamine was shown to be diastereo-specific with formation primarily of the (1S*,4R*) diastereomer of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-β-carboline, a compound with potential GABA-receptor activity.
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Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 468–470, September–October, 2006.
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Semenov, B.B., Novikov, K.A., Kachala, V.V. et al. Synthesis of 4-phenyl-1-(2-thienyl)-2,3,4,9-tetrahydro-1H-β-carboline. Chem Nat Compd 42, 582–584 (2006). https://doi.org/10.1007/s10600-006-0218-z
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DOI: https://doi.org/10.1007/s10600-006-0218-z