We consider the construction of high-resolution images from a time series of fluorescence microscopy images obtained using a scintillator. A regularization method is applied and the results are compared for various stabilizers, including the RED (regularization-by-denoising) approach. Tests conducted for two series of microtubule structures have proved the applicability of the proposed methods.
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Translated from Prikladnaya Matematika i Informatika, No. 66, 2021, pp. 5–14.
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Pchelintsev, I.A., Nasonov, A.V. & Krylov, A.S. Regularization Methods in the Analysis of a Series of Scintillation Fluorescence Microscopy Images. Comput Math Model 32, 111–119 (2021). https://doi.org/10.1007/s10598-021-09520-3
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DOI: https://doi.org/10.1007/s10598-021-09520-3