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Synthesis of functionalized triazolo[1,5-a]pyrimidine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

New triazolo[1,5-a]pyrimidines containing aroyl and acetyl or ester groups in the pyrimidine ring were synthesized in a process related to the Biginelli-like reaction, using hydrates of arylglyoxals, β-dicarbonyl compounds, and 1H-1,2,4-triazol-5-amine. Reaction was carried out in either sequential or one-pot procedure.

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Authors and Affiliations

  1. V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61022, Ukraine

    Natal’ya V. Chechina & Nadezhda N. Kolos

  2. STC “Institute of Single Crystals”, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61072, Ukraine

    Irina V. Omelchenko & Vladimir I. Musatov

Authors
  1. Natal’ya V. Chechina
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  2. Nadezhda N. Kolos
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  3. Irina V. Omelchenko
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  4. Vladimir I. Musatov
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Corresponding author

Correspondence to Nadezhda N. Kolos.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(1), 58–62

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Chechina, N.V., Kolos, N.N., Omelchenko, I.V. et al. Synthesis of functionalized triazolo[1,5-a]pyrimidine derivatives. Chem Heterocycl Comp 54, 58–62 (2018). https://doi.org/10.1007/s10593-018-2230-1

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  • DOI: https://doi.org/10.1007/s10593-018-2230-1

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