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Diaryl-Substituted Polyethers with Acetoacet-Anilide Fragment in the Synthesis of Dihydro-Pyrimidine-Containing Podands*

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Chemistry of Heterocyclic Compounds Aims and scope

The interaction of ortho-aminoaryl polyethers, derivatives of mono-, di-, and triethylene glycol, with acetyl ketene, generated from 2,2,6-trimethyl-4H-1,3-dioxin-4-one produced acetoacetanilide- containing podands. 2,2,6-Trimethyl-4H-1,3-dioxin-4-one reacted with aminoaryl-substituted podands containing a short polyether chain (1-2 atoms) in toluene medium without catalyst. Acetoacetanilide- containing podands with longer polyether chains could be obtained by using triethylamine or acetic acid as catalyst. Acetoacetanilide-containing podands were used in the Biginelli reaction as СН-active components.

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Authors and Affiliations

  1. Ural Federal University named after the First President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg, 620002, Russia

    E. S. Radionova, Yu. A. Titova, O. V. Fedorova, G. L. Rusinov & V. N. Charushin

  2. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, 22 S. Kovalevskoi St. / 20 Akademicheskaya St., Yekaterinburg, 620990, Russia

    Yu. A. Titova, M. L. Isenov, O. V. Fedorova, G. L. Rusinov & V. N. Charushin

Authors
  1. E. S. Radionova
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  2. Yu. A. Titova
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  3. M. L. Isenov
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  4. O. V. Fedorova
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  5. G. L. Rusinov
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  6. V. N. Charushin
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Corresponding author

Correspondence to E. S. Radionova.

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Dedicated to Academician O. N. Chupakhin on the occasion of his 80th birthday.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1083-1089, July, 2014.

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Radionova, E.S., Titova, Y.A., Isenov, M.L. et al. Diaryl-Substituted Polyethers with Acetoacet-Anilide Fragment in the Synthesis of Dihydro-Pyrimidine-Containing Podands* . Chem Heterocycl Comp 50, 998–1004 (2014). https://doi.org/10.1007/s10593-014-1555-7

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  • DOI: https://doi.org/10.1007/s10593-014-1555-7

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