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Phenylglyoxal dihydrazones as unexpected products in the synthesis of 1,2,4-triazines by interaction of α-bromoacetophenones and arylhydrazides

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Chemistry of Heterocyclic Compounds Aims and scope

On interacting α-bromoacetophenones with aromatic carboxylic acid hydrazides, the formation of two reaction products was observed in certain cases, the expected 1,2,4-triazine and the phenylglyoxal dihydrazone as an unexpected product. The effect of substituents in the initial substrates and of the conditions of carrying out the synthesis on the direction of the reaction have been studied.

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Authors and Affiliations

  1. Ural Federal University named after the First President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg, 620002, Russia

    D. S. Kopchuk, I. S. Kovalev, G. V. Zyryanov, A. F. Khasanov, A. S. Medvedevskikh, V. L. Rusinov & O. N. Chupakhin

  2. I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi St.,/ 20 Akademicheskaya St., Yekaterinburg, 620219, Russia

    D. S. Kopchuk, G. V. Zyryanov, V. L. Rusinov & O. N. Chupakhin

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  1. D. S. Kopchuk
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  2. I. S. Kovalev
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  3. G. V. Zyryanov
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  4. A. F. Khasanov
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  5. A. S. Medvedevskikh
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  6. V. L. Rusinov
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  7. O. N. Chupakhin
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Correspondence to D. S. Kopchuk.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1060-1064, July, 2013.

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Kopchuk, D.S., Kovalev, I.S., Zyryanov, G.V. et al. Phenylglyoxal dihydrazones as unexpected products in the synthesis of 1,2,4-triazines by interaction of α-bromoacetophenones and arylhydrazides . Chem Heterocycl Comp 49, 988–992 (2013). https://doi.org/10.1007/s10593-013-1336-8

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  • DOI: https://doi.org/10.1007/s10593-013-1336-8

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