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Acetamidines and acetamidoximes containing an electron-withdrawing group at the α-carbon atom: their use in the synthesis of nitrogen heterocycles (review)*

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Chemistry of Heterocyclic Compounds Aims and scope

Published information on heterocyclizations involving acetamidines and acetamidoximes substituted at the α-position with an electron-withdrawing group is reviewed, where these starting materials have been used in the synthesis of 2-aminoazaheterocycles (2-aminopyridines, 2-aminopyrroles, and 2-aminoazirines). In such reactions the α-carbon atom of the amidine or amidoxime is included in the ring of the obtained heterocycle.

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  1. Saint Petersburg State University, 26 Universitetskii Ave., Saint Petersburg, 198504, Russia

    P. S. Lobanov & D. V. Dar’in

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*In memory of our tutor Prof. Anatolii Alekseevich Potekhin, who would have been 75 years old on May 12 this year.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 546–567, April, 2013.

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Lobanov, P.S., Dar’in, D.V. Acetamidines and acetamidoximes containing an electron-withdrawing group at the α-carbon atom: their use in the synthesis of nitrogen heterocycles (review)*. Chem Heterocycl Comp 49, 507–528 (2013). https://doi.org/10.1007/s10593-013-1277-2

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