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New method for the direct electrophilic amination of aromatic compounds and its use in the annelation of the pyrimidine ring

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Chemistry of Heterocyclic Compounds Aims and scope

A method has been developed for the synthesis of aromatic amines by the amination of the corresponding aromatic compounds using sodium azide in PPA. A method for the synthesis of quinazolines and benzo[h]quinazolines using this reaction and the subsequent reaction of the intermediates with 1,3,5-triazines has been developed.

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Notes

  1. * Reported in our preliminary communication [4].

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Authors and Affiliations

  1. Stavropol State University, Stavropol, 355009, Russia

    A. V. Aksenov, A. S. Lyakhovnenko & M. M. Kugutov

Authors
  1. A. V. Aksenov
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  2. A. S. Lyakhovnenko
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  3. M. M. Kugutov
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Correspondence to A. V. Aksenov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1559-1562, October, 2010.

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Aksenov, A.V., Lyakhovnenko, A.S. & Kugutov, M.M. New method for the direct electrophilic amination of aromatic compounds and its use in the annelation of the pyrimidine ring. Chem Heterocycl Comp 46, 1262–1265 (2011). https://doi.org/10.1007/s10593-011-0661-z

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  • DOI: https://doi.org/10.1007/s10593-011-0661-z

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