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Synthesis and crystal structure of 2,6-bis(N-cytisinomethyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester

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Chemistry of Heterocyclic Compounds Aims and scope

By the interaction of the diethyl ester of 2,6-bis(bromomethyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid with two moles of the alkaloid cytosine, the corresponding 2,6-bis(cytisinomethyl) derivative was obtained. The spatial structure of the product was demonstrated by 1H NMR spectroscopy and X-ray structural analysis.

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Authors and Affiliations

  1. Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda, 100008, Kazakhstan

    I. V. Kulakov

  2. International Scientific and Production Holding ʽʽPhytochemistryʼʼ, Karaganda, 100009, Kazakhstan

    D. M. Turdybekov

Authors
  1. I. V. Kulakov
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  2. D. M. Turdybekov
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Correspondence to I. V. Kulakov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1039-1043, July, 2010.

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Kulakov, I.V., Turdybekov, D.M. Synthesis and crystal structure of 2,6-bis(N-cytisinomethyl)-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester. Chem Heterocycl Comp 46, 839–843 (2010). https://doi.org/10.1007/s10593-010-0591-1

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