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Interaction of secondary amines with aromatic aldehydes-efficient method for synthesis of the functionalized heterocyclic amines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A method is proposed for the benzylation of secondary heterocyclic amines with functionalized derivatives of benzaldehyde in the presence of formic acid under conditions close to amination according to the Leuckart-Wallach reaction.

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Authors and Affiliations

  1. Institute of the Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk, 220141

    Zh. V. Ignatovich, K. N. Gusak, T. V. Chernikhova & E. V. Koroleva

  2. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Minsk, 220072

    N. G. Kozlov

Authors
  1. Zh. V. Ignatovich
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  2. K. N. Gusak
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  3. T. V. Chernikhova
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  4. N. G. Kozlov
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  5. E. V. Koroleva
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Corresponding author

Correspondence to E. V. Koroleva.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1820–1823, December, 2007.

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Ignatovich, Z.V., Gusak, K.N., Chernikhova, T.V. et al. Interaction of secondary amines with aromatic aldehydes-efficient method for synthesis of the functionalized heterocyclic amines. Chem Heterocycl Comp 43, 1540–1543 (2007). https://doi.org/10.1007/s10593-007-0238-z

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  • DOI: https://doi.org/10.1007/s10593-007-0238-z

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