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α-Ureidoalkylation of 1,3-bis(hydroxymethyl)-imidazolidin-2-one

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The α-ureidoalkylation of imidazolidine-2,4-dione, urea, carboxylic acid amides, and sulfonamides has been studied using 1,3-bis(hydroxymethyl)-imidazolidin-2-one as ureidoalkylating agent. Methods have been developed for the synthesis of 1,3-bis(2,4-dioxoimidazolidin-1-ylmethyl)-, 1,3-bis(acetylaminomethyl)-, 1,3-bis(benzoylaminomethyl)-, 1,3-bis(phenylsulfonylaminomethyl)-, and 1,3-bis(p-toluenesulfonylaminomethyl)imidazolidin-2-ones.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991

    G. A. Gazieva, P. V. Lozhkin & A. N. Kravchenko

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  1. G. A. Gazieva
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  2. P. V. Lozhkin
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  3. A. N. Kravchenko
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Correspondence to G. A. Gazieva.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1655–1659, November, 2007.

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Gazieva, G.A., Lozhkin, P.V. & Kravchenko, A.N. α-Ureidoalkylation of 1,3-bis(hydroxymethyl)-imidazolidin-2-one. Chem Heterocycl Comp 43, 1406–1410 (2007). https://doi.org/10.1007/s10593-007-0217-4

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  • DOI: https://doi.org/10.1007/s10593-007-0217-4

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