Skip to main content

Advertisement

Log in

Role of Maternal Depression on Child Development: A Prospective Analysis from Pregnancy to Early Childhood

  • Original Article
  • Published:
Child Psychiatry & Human Development Aims and scope Submit manuscript

Abstract

Few studies have examined how different characteristics of maternal depression may be associated with developmental outcomes among low-income children. The current study prospectively examined whether the timing (pregnancy vs. early postpartum), severity, and chronicity of maternal depression were associated with child cognitive and social-emotional development in two cohorts of primarily low-income Latinx immigrant mothers and their children. Maternal depression was assessed during pregnancy and at 6 months postpartum. Child development was assessed up to 5 years postpartum. Results showed that maternal depression experienced during pregnancy was associated with lower child cognitive development, particularly among girls. Additionally, both the timing (pregnancy and early postpartum) and severity/chronicity of maternal depression were each independently associated with lower child social-emotional development. These findings highlight the need for early prevention interventions to help offset the adverse effects of maternal depression on child developmental outcomes in this at-risk population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Accortt EE, Freeman MP, Allen JJ (2008) Women and major depressive disorder: clinical perspectives on causal pathways. J Womens Health (Larchmt) 17(10):1583–1590. https://doi.org/10.1089/jwh.2007.0592

    Article  Google Scholar 

  2. Biaggi A, Conroy S, Pawlby S, Pariante CM (2016) Identifying the women at risk of antenatal anxiety and depression: a systematic review. J Affect Disord 191:62–77. https://doi.org/10.1016/j.jad.2015.11.014

    Article  PubMed  PubMed Central  Google Scholar 

  3. D’Anna-Hernandez KL, Aleman B, Flores AM (2015) Acculturative stress negatively impacts maternal depressive symptoms in Mexican-American women during pregnancy. J Affect Disord 176:35–42. https://doi.org/10.1016/j.jad.2015.01.036

    Article  PubMed  PubMed Central  Google Scholar 

  4. Alhasanat D, Giurgescu C (2017) Acculturation and postpartum depressive symptoms among Hispanic women in the United States: systematic review. MCN Am J Matern Child Nurs 42(1):21–28. https://doi.org/10.1097/NMC.0000000000000298

    Article  PubMed  Google Scholar 

  5. National Academies of Sciences, Engineering, and Medicine (2019) Fostering healthy mental, emotional, and behavioral development in children and youth: a national agenda. The National Academies Press, Washington, DChttps://doi.org/10.17226/25201

    Book  Google Scholar 

  6. Grace S, Evindar A, Stewart D (2003) The effect of postpartum depression on child cognitive development and behavior: a review and critical analysis of the literature. Arch Womens Ment Health 6:263–274. https://doi.org/10.1007/s00737-003-0024-6

    Article  PubMed  Google Scholar 

  7. Guyon-Harris K, Huth-Bocks A, Lauterbach D, Janisse H (2016) Trajectories of maternal depressive symptoms across the birth of a child: associations with toddler emotional development. Arch Womens Ment Health 19(1):153–165. https://doi.org/10.1007/s00737-015-0546-8

    Article  PubMed  Google Scholar 

  8. Kingston D, Tough S, Whitfield H (2012) Prenatal and postpartum maternal psychological distress and infant development: a systematic review. Child Psychiatry Hum Dev 43(5):683–714. https://doi.org/10.1007/s10578-012-0291-4

    Article  PubMed  Google Scholar 

  9. Sohr-Preston SL, Scaramella LV (2006) Implications of timing of maternal depressive symptoms for early cognitive and language development. Clin Child Fam Psychol Rev 9(1):65–83. https://doi.org/10.1007/s10567-006-0004-2

    Article  PubMed  Google Scholar 

  10. Barker DJ (1998) In utero programming of chronic disease. Clin Sci (Lond) 95(2):115–128

    Article  Google Scholar 

  11. Waters CS, Hay DF, Simmonds JR, van Goozen SH (2014) Antenatal depression and children’s developmental outcomes: potential mechanisms and treatment options. Eur Child Adolesc Psychiatry 23(10):957–971. https://doi.org/10.1007/s00787-014-0582-3

    Article  PubMed  Google Scholar 

  12. Koutra K, Chatzi L, Bagkeris M, Vassilaki M, Bitsios P, Kogevinas M (2013) Antenatal and postnatal maternal mental health as determinants of infant neurodevelopment at 18 months of age in a mother-child cohort (Rhea Study) in Crete Greece. Soc Psychiatry Psychiatr Epidemiol 48(8):1335–1345. https://doi.org/10.1007/s00127-012-0636-0

    Article  PubMed  Google Scholar 

  13. Evans J, Melotti R, Heron J et al (2012) The timing of maternal depressive symptoms and child cognitive development: a longitudinal study. J Child Psychol Psychiatry 53(6):632–640. https://doi.org/10.1111/j.1469-7610.2011.02513.x

    Article  PubMed  Google Scholar 

  14. Junge C, Garthus-Niegel S, Slinning K, Polte C, Simonsen TB, Eberhard-Gran M (2017) The impact of perinatal depression on children’s social-emotional development: a longitudinal study. Matern Child Health J 21(3):607–615. https://doi.org/10.1007/s10995-016-2146-2

    Article  PubMed  Google Scholar 

  15. Woolhouse H, Gartland D, Mensah F, Giallo R, Brown S (2016) Maternal depression from pregnancy to 4 years postpartum and emotional/behavioural difficulties in children: results from a prospective pregnancy cohort study. Arch Womens Ment Health 19(1):141–151. https://doi.org/10.1007/s00737-015-0562-8

    Article  PubMed  Google Scholar 

  16. Porter E, Lewis AJ, Watson SJ, Galbally M (2019) Perinatal maternal mental health and infant socio-emotional development: a growth curve analysis using the MPEWS cohort. Infant Behav Dev 57:101336. https://doi.org/10.1016/j.infbeh.2019.101336

    Article  PubMed  Google Scholar 

  17. Aoyagi SS, Tsuchiya KJ (2019) Does maternal postpartum depression affect children’s developmental outcomes? J Obstet Gynaecol Res 45(9):1809–1820. https://doi.org/10.1111/jog.14064

    Article  PubMed  Google Scholar 

  18. Brennan PA, Hammen C, Andersen MJ, Bor W, Najman JM, Williams GM (2000) Chronicity, severity, and timing of maternal depressive symptoms: relationships with child outcomes at age 5. Dev Psychol 36(6):759–766. https://doi.org/10.1037//0012-1649.36.6.759

    Article  PubMed  Google Scholar 

  19. Kim DJ, Davis EP, Sandman CA, Sporns O, O’Donnell BF, Buss C, Hetrick WP (2017) Prenatal maternal cortisol has sex-specific associations with child brain network properties. Cereb Cortex 27(11):5230–5241. https://doi.org/10.1093/cercor/bhw303

    Article  PubMed  Google Scholar 

  20. Sandman CA, Glynn LM, Davis EP (2013) Is there a viability-vulnerability tradeoff? Sex differences in fetal programming. J Psychosom Res 75(4):327–335. https://doi.org/10.1016/j.jpsychores.2013.07.009

    Article  PubMed  PubMed Central  Google Scholar 

  21. Petterson SM, Albers AB (2001) Effects of poverty and maternal depression on early child development. Child Dev 72(6):1794–1813. https://doi.org/10.1111/1467-8624.00379

    Article  PubMed  Google Scholar 

  22. Jensen SK, Dumontheil I, Barker ED (2014) Developmental inter-relations between early maternal depression, contextual risks, and interpersonal stress, and their effect on later child cognitive functioning. Depress Anxiety 31(7):599–607. https://doi.org/10.1002/da.22147

    Article  PubMed  Google Scholar 

  23. National Institute of Child Health and Human Development Early Child Care Research Network (2005) Duration and developmental timing of poverty and children’s cognitive and social development from birth through third grade. Child Dev 76(4):795–810. https://doi.org/10.1111/j.1467-8624.2005.00878.x

    Article  Google Scholar 

  24. Pew Research Center (2017). Pew Research Center tabulations of 1960–2000 decennial censuses and 2010, 2013–2017. American Community Surveys (IPUMS).

  25. US Census Bureau (2019). US Census Demographic Profiles. Washington, D.C.

  26. Washbrook E, Waldfogel J, Bradbury B, Corak M, Ghanghro AA (2012) The development of young children of immigrants in Australia, Canada, the United Kingdom, and the United States. Child Dev 83(5):1591–1607. https://doi.org/10.1111/j.1467-8624.2012.01796.x

    Article  PubMed  PubMed Central  Google Scholar 

  27. Vega WA, Kolody B, Aguilar-Gaxiola S, Alderete E, Catalano R, Caraveo-Anduaga J (1998) Lifetime prevalence of DSM-III-R psychiatric disorders among urban and rural Mexican Americans in California. Arch Gen Psychiatry 55(9):771–778. https://doi.org/10.1001/archpsyc.55.9.771

    Article  PubMed  Google Scholar 

  28. US Census Bureau (2000). US Census Demographic Profiles. Washington, D.C.

  29. Le H, Muñoz RF, Soto JA, Delucchi KL, Ghosh-Ippen C (2004) Identifying risk for onset of major depressive episodes in low-income Latinas during pregnancy and postpartum. Hisp J Behav Sci 26(4):463–482

    Article  Google Scholar 

  30. Muñoz RF, Le H, Ippen CG, Diaz MA, Urizar GG Jr, Soto J, Lieberman AF (2007) Prevention of postpartum depression in low-income women: development of the Mamás y Bebés/ Mothers and Babies Course. Cogn Behav Pract 14(1):70–83

    Article  Google Scholar 

  31. Urizar GG Jr, Muñoz RF (2011) Impact of a prenatal cognitive-behavioral stress management intervention on salivary cortisol levels in low-income mothers and their infants. Psychoneuroendocrinology 36(10):1480–1494. https://doi.org/10.1016/j.psyneuen.2011.04.002

    Article  PubMed  PubMed Central  Google Scholar 

  32. Radloff LS (1977) The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1:385–401

    Article  Google Scholar 

  33. Guarnaccia PJ, Angel R, Worobey JL (1989) The factor structure of the CES-D in the Hispanic Health and Nutrition Examination Survey: the influences of ethnicity, gender and language. Soc Sci Med 29(1):85–94. https://doi.org/10.1016/0277-9536(89)90131-7

    Article  PubMed  Google Scholar 

  34. Zich JM, Attkisson CC, Greenfield TK (1990) Screening for depression in primary care clinics: the CES-D and the BDI. Int J Psychiatry Med 20(3):259–277. https://doi.org/10.2190/LYKR-7VHP-YJEM-MKM2

    Article  PubMed  Google Scholar 

  35. Mullen EM (1995) Mullen Scales of Early Learning. AGS American Guidance Service Inc., Circle Pines, MN

    Google Scholar 

  36. Crosby FX (1999). A comparative study of the Mullen Scales of Early Learning with Hispanic infants. ProQuest Dissertations and Theses: The Humanities and Social Sciences Collection.

  37. Sparrow SS, Balla DA, Cicchetti DV (1998) Vineland Social-Emotional Early Childhood Scales. American Guidance Services, Circle Pines, MN

    Google Scholar 

  38. Faul F, Erdfelder E, Buchner A, Lang AG (2009) Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods 41(4):1149–1160. https://doi.org/10.3758/BRM.41.4.1149

    Article  PubMed  Google Scholar 

  39. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Lawrence Earlbaum Associates, Hillsdale, NJ

    Google Scholar 

  40. Davis EP, Sandman CA (2010) The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development. Child Dev 81(1):131–148. https://doi.org/10.1111/j.1467-8624.2009.01385.x

    Article  PubMed  PubMed Central  Google Scholar 

  41. Ellman LM, Schetter CD, Hobel CJ, Chicz-Demet A, Glynn LM, Sandman CA (2008) Timing of fetal exposure to stress hormones: effects on newborn physical and neuromuscular maturation. Dev Psychobiol 50(3):232–241. https://doi.org/10.1002/dev.20293

    Article  PubMed  PubMed Central  Google Scholar 

  42. Buss C, Davis EP, Shahbaba B, Pruessner JC, Head K, Sandman CA (2012) Maternal cortisol over the course of pregnancy and subsequent child amygdala and hippocampus volumes and affective problems. Proc Natl Acad Sci U S A 109(20):E1312–E1319. https://doi.org/10.1073/pnas.1201295109

    Article  PubMed  PubMed Central  Google Scholar 

  43. Chang M, Park B, Singh K, Sung YY (2009) Parental involvement, parenting behaviors, and children’s cognitive development in low-income and minority families. J Res Child Edu 23(3):309–324. https://doi.org/10.1080/02568540909594663

    Article  Google Scholar 

  44. O’Hara MW (2009) Postpartum depression: what we know. J Clin Psychol 65(12):1258–1269. https://doi.org/10.1002/jclp.20644

    Article  PubMed  Google Scholar 

  45. US Preventive Services Task Force (2019) Interventions to prevent perinatal depression: US Preventive Services Task Force recommendation statement. JAMA 321(6):580–587. https://doi.org/10.1001/jama.2019.0007

    Article  Google Scholar 

  46. Fuller B, García CC (2010) Learning from Latinos: contexts, families, and child development in motion. Dev Psychol 46(3):559–565. https://doi.org/10.1037/a0019412

    Article  PubMed  Google Scholar 

  47. Muñoz RF, Cuijpers P, Smit F, Barrera AZ, Leykin Y (2010) Prevention of major depression. Annu Rev Clin Psychol 6:181–212. https://doi.org/10.1146/annurev-clinpsy-033109-132040

    Article  PubMed  Google Scholar 

  48. Muñoz RF, Beardslee WR, Leykin Y (2012) Major depression can be prevented. Am Psychol 67(4):285–295. https://doi.org/10.1037/a0027666

    Article  PubMed  PubMed Central  Google Scholar 

  49. Muñoz RF (2019) Prevent depression in pregnancy to boost all mental health. Nature 574(7780):631–633. https://doi.org/10.1038/d41586-019-03226-8

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

Guido G. Urizar Jr. is in the Department of Psychology, California State University, Long Beach. Ricardo F. Muñoz is Director of the Institute for International Internet Interventions for Health and Distinguished Professor in the Department of Psychology, Palo Alto University and Professor of Psychology, Emeritus at the University of California, San Francisco (UCSF) Department of Psychiatry at San Francisco General Hospital.

Funding

This study was conducted at San Francisco General Hospital, UCSF School of Medicine and was supported by a University of California Mexico-U.S. (UC MEXUS) Research Grant (UC MEXUS SCR 43; Ricardo F. Muñoz & Guido G. Urizar Jr., Co-PIs). Additional support was provided by grants from the National Institute of Mental Health (MH 596056, Ricardo F. Muñoz, PI), the University of California Office of the President’s Committee on Latino Research for the UCSF/San Francisco General Hospital Latino Mental Health Research Program (Ricardo F. Muñoz, PI), the Research and Evaluation Allocation Committee of the UCSF School of Medicine, and by private donations from Dr. Cloyce L. Duncan and Dr. Gwendolyn Evans for the Mamás y Bebés/Mothers and Babies: Mood and Health Project. The authors gratefully acknowledge the contributions of Huynh-Nhu (Mimi) Le, Chandra Ghosh Ippen, Paula Valenzuela, Mercy Somera, Rosario Sotelo, and Theresita Solomon and the rest of the Latino Mental Health Research Program team for their instrumental support with data collection. At the time this study was conducted, G. Urizar was funded as a postdoctoral fellow by the UCSF Clinical Psychology Training Program.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Guido G. Urizar Jr..

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Urizar, G.G., Muñoz, R.F. Role of Maternal Depression on Child Development: A Prospective Analysis from Pregnancy to Early Childhood. Child Psychiatry Hum Dev 53, 502–514 (2022). https://doi.org/10.1007/s10578-021-01138-1

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10578-021-01138-1

Keywords

Navigation