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Nanocellulose conjugated with retinoic acid: its capability to adsorb aflatoxin B1

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An Erratum to this article was published on 02 April 2015

Abstract

The main aim of this study was to evaluate the adsorption of aflatoxin B1 by nanocellulose conjugated with retinoic acid (NCRA). First, aflatoxin B1 and NCRA were modeled in the Hyperchem software, and then the adsorption of aflatoxin B1 was simulated by the molecular dynamics technique. Second, nanocellulose was synthesized and conjugated with retinoic acid by cross-linker. Third, the adsorption of aflatoxin B1 and NCRA and its release were evaluated at different conditions. Fourth, its adsorption was evaluated in different foodstuffs. Sixth, its toxicity was evaluated on mouse esophageal cells (MECs). Computer-based simulation showed the adsorption of aflatoxin B1 by NCRA. This study showed that the adsorption and release were less affected by temperature and incubation time but highly affected by pH and concentration. Moreover, it was found that NCRA could adsorb aflatoxin B1 in different foodstuffs. Importantly, NCRA had no remarkable toxicity on the MECs.

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Acknowledgments

This article was extracted from the M.Sc thesis of Najme Sedighi and financially supported by the Department of Medical Nanotechnology, Pajoohesh Laboratory, Yazd, Iran. The authors thank the laboratory staff of the Yazd Pajoohesh Medical laboratory.

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The authors declare no conflict of interest.

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Authors and Affiliations

  1. Department of Medical Genetic, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Ali Jebali

  2. Department of Food Science, College of Agriculture, Islamic Azad University, 8916733754, Yazd, Iran

    Ali Jebali, Seyed Ali Yasini Ardakani & Najme Sedighi

  3. Department of Laboratory Sciences, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

    Seyedhossein Hekmatimoghaddam

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  1. Ali Jebali
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  2. Seyed Ali Yasini Ardakani
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  3. Najme Sedighi
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  4. Seyedhossein Hekmatimoghaddam
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Correspondence to Seyed Ali Yasini Ardakani.

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Jebali, A., Yasini Ardakani, S.A., Sedighi, N. et al. Nanocellulose conjugated with retinoic acid: its capability to adsorb aflatoxin B1. Cellulose 22, 363–372 (2015). https://doi.org/10.1007/s10570-014-0475-0

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  • DOI: https://doi.org/10.1007/s10570-014-0475-0

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