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Surface modification of oxidized cellulose haemostat by argon plasma treatment

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Abstract

In this paper we focused on cold plasma treatment of oxidized cellulose haemostat. Oxidized cellulose was modified in inert argon plasma. The changes of surface composition were examined by XPS and FTIR. Surface morphology of fibres was studied by SEM. Gravimetry was used to study ablation and water absorption. Antibacterial effect of pristine and plasma treated samples was examined by growth of Escherichia coli and Staphylococcus epidermidis. Behaviour of pristine and plasma treated samples in water, physiological saline solution and phosphate buffered saline was observed by changes in the pH of their solutions. Modification of oxidized cellulose by inert argon plasma caused significant changes in the chemical composition of its surface layers as well as changes in morphology of those layers while maintaining or improving the antibacterial properties. We found out that modification by inert argon plasma improves the properties necessary for haemostatic function of oxidized cellulose.

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Acknowledgments

This work was financially supported by GA CR under the project No. P108/12/1168.

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Authors and Affiliations

  1. Department of Solid State Engineering, ICT Prague, Technická 5, 166 28, Prague, Czech Republic

    Vladimíra Vosmanska, Katerina Kolarova & Vaclav Svorcik

  2. Department of Biochemistry and Microbiology, ICT Prague, Technická 5, 166 28, Prague, Czech Republic

    Silvie Rimpelova

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  1. Vladimíra Vosmanska
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  2. Katerina Kolarova
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  3. Silvie Rimpelova
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  4. Vaclav Svorcik
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Correspondence to Vladimíra Vosmanska.

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Vosmanska, V., Kolarova, K., Rimpelova, S. et al. Surface modification of oxidized cellulose haemostat by argon plasma treatment. Cellulose 21, 2445–2456 (2014). https://doi.org/10.1007/s10570-014-0328-x

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