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Heck Reactions of Aryl Chlorides Catalyzed by Ligand Free Palladium Salts

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Abstract

Palladium acetate has been shown to be a highly active catalyst for Heck reactions of aryl chlorides even in the absence of organic ligands. Bromobenzene can efficiently be coupled in presence of negligible traces of Pd, resulting in the highest TON (4.7 × 107) and TOF (1.2 × 107 h−1) values that have ever been reported for this system up to now.

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Acknowledgments

Manfred Barth and his co-workers (Mikroanalytisches Labor, TU München) are gratefully acknowledged for the performance of Pd trace analysis

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Authors and Affiliations

  1. Department of Chemistry, Technische Universität München, Lichtenbergstr. 4, Garching, 85747, Germany

    Wolfgang Kleist, Sandra S. Pröckl & Klaus Köhler

  2. Institute for Chemical and Bioengineering, ETH Zurich, Wolfgang-Pauli-Str. 10, Zurich, 8093, Switzerland

    Wolfgang Kleist

Authors
  1. Wolfgang Kleist
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  2. Sandra S. Pröckl
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  3. Klaus Köhler
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Correspondence to Klaus Köhler.

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Kleist, W., Pröckl, S.S. & Köhler, K. Heck Reactions of Aryl Chlorides Catalyzed by Ligand Free Palladium Salts. Catal Lett 125, 197–200 (2008). https://doi.org/10.1007/s10562-008-9533-2

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  • DOI: https://doi.org/10.1007/s10562-008-9533-2

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