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A feedback control systems view of epileptic seizures

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Cybernetics and Systems Analysis Aims and scope

Abstract

To understand basic functional mechanisms that cause epileptic seizures, the paper discusses some key features of theoretical brain functioning models. The hypothesis is put forward that a plausible reason for seizures is pathological feedback in brain circuitry. The analysis of such circuitry has an interesting physical interpretation and may be used to cure epilepsy.

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Author information

Authors and Affiliations

  1. Department of Electrical Engineering, Arizona State University, USA

    K. Tsakalis, N. Chakravarthy & Sh. Sabesan

  2. Harrington Department of Bioengineering, Arizona State University, USA

    L. D. Iasemidis

  3. Department of Industrial and Systems Engineering, Department of Biomedical Engineering and McKnight Brain Institute, University of Florida, USA

    P. M. Pardalos

Authors
  1. K. Tsakalis
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  2. N. Chakravarthy
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  3. Sh. Sabesan
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  4. L. D. Iasemidis
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  5. P. M. Pardalos
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Additional information

The paper is dedicated to the 70th birthday of Academician I. V. Sergienko.

Published in Kibernetika i Sistemnyi Analiz, No. 4, pp. 26–40, July–August 2006.

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Tsakalis, K., Chakravarthy, N., Sabesan, S. et al. A feedback control systems view of epileptic seizures. Cybern Syst Anal 42, 483–495 (2006). https://doi.org/10.1007/s10559-006-0087-2

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  • DOI: https://doi.org/10.1007/s10559-006-0087-2

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