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High-resolution systolic T1 mapping with compressed sensing for the evaluation of the right ventricle: a phantom and volunteer study

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Abstract

To investigate the usefulness of high-resolution systolic T1 mapping using compressed sensing for right ventricular (RV) evaluation. Phantoms and normal volunteers were scanned at 3 T by using a high-resolution (HR) modified look-locker inversion recovery (MOLLI) pulse sequence and a conventional MOLLI pulse sequence. The T1 values of the left ventricular (LV) and RV myocardium and blood pool were measured for each sequence. T1 values of HR-MOLLI and MOLLI sequences were compared in the LV myocardium, blood pool, and RV myocardium. The T1 values of HR-MOLLI and MOLLI showed good agreement in both phantoms and the LV myocardium and blood pool of volunteers. However, there was a significant difference between HR-MOLLI and MOLLI in the RV myocardium (1258 ± 52 ms vs. 1327 ± 73 ms; P = 0.0005). No significant difference was observed between the T1 value of RV and that of LV (1217 ± 32 ms) in HR-MOLLI, whereas the T1 value of RV was significantly higher than that of LV in MOLLI (P < 0.0001). The interclass correlation coefficients of intraobserver variabilities from HR-MOLLI and MOLLI were 0.919 and 0.804, respectively, and the interobserver variabilities from HR-MOLLI and MOLLI were 0.838 and 0.848, respectively. Assessment of RV myocardium by using HR systolic T1 mapping was superior to the conventional MOLLI sequence in terms of accuracy and reproducibility.

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Funding

This work was supported by the research grant from KONICAMINOLTA, the Japan Society for the Promotion of Science (JSPS) KAKENHI (20K16728), the research grant of the Japanese Radiological Society from Bayer (KJ-2019-2) and Konica Minolta Imaging Science Encouragement Award from Konica Minolta Science and Technology Foundation.

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Authors and Affiliations

  1. Division of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan

    Daisuke Nishigake, Ryohei Funatsu, Tatsuhiro Wada, Masahiro Oga, Koji Kobayashi & Toyoyuki Kato

  2. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Yuzo Yamasaki & Kousei Ishigami

  3. Department of Perinatal and Pediatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Kenichiro Yamamura

Authors
  1. Daisuke Nishigake
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  2. Yuzo Yamasaki
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  3. Kenichiro Yamamura
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  4. Ryohei Funatsu
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  5. Tatsuhiro Wada
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  6. Masahiro Oga
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  7. Koji Kobayashi
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  8. Toyoyuki Kato
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  9. Kousei Ishigami
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by DN and YY. The first draft of the manuscript was written by DN and all authors commented on previous versions of the manuscript. All authors have read and approved the final manuscript.

Corresponding author

Correspondence to Yuzo Yamasaki.

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The authors declare that they have no conflict of interest.

Ethical approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University Kyushu (No2020-579).

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Informed consent was obtained from all individual participants included in the study.

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Nishigake, D., Yamasaki, Y., Yamamura, K. et al. High-resolution systolic T1 mapping with compressed sensing for the evaluation of the right ventricle: a phantom and volunteer study. Int J Cardiovasc Imaging 38, 2219–2225 (2022). https://doi.org/10.1007/s10554-022-02622-y

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  • DOI: https://doi.org/10.1007/s10554-022-02622-y

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