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Can we HIIT cancer if we attack inflammation?

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Abstract

Physical exercise offers numerous health-related benefits to individuals with cancer. Epidemiologic research has primarily been concerned with conventional exercise training that aligns with the recommendations of 150 min of moderate to vigorous physical activity per week. These recommendations are safe and effective at improving physical and psychosocial outcomes. Given the extensive evidence for generalized physical activity, researchers have begun to explore novel training regimens that may provide additional health benefits and/or improved adherence. Specifically, exercise at higher intensities may offer more or different benefits than conventional training approaches with potentially profound effects on the tumor microenvironment. This commentary focuses on the physiological effects of high-intensity interval training, also known as “HIIT,” and its potential antineoplastic properties.

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Authors and Affiliations

  1. Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada

    Efthymios Papadopoulos & Daniel Santa Mina

  2. Cancer Rehabilitation and Survivorship, Princess Margaret Cancer Centre, Toronto, ON, Canada

    Efthymios Papadopoulos & Daniel Santa Mina

Authors
  1. Efthymios Papadopoulos
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  2. Daniel Santa Mina
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Correspondence to Daniel Santa Mina.

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Papadopoulos, E., Santa Mina, D. Can we HIIT cancer if we attack inflammation?. Cancer Causes Control 29, 7–11 (2018). https://doi.org/10.1007/s10552-017-0983-y

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